PMID- 18246698
OWN - NLM
STAT- MEDLINE
DCOM- 20080505
LR  - 20151119
IS  - 1545-9616 (Print)
IS  - 1545-9616 (Linking)
VI  - 7
IP  - 1
DP  - 2008 Jan
TI  - Primary cutaneous Cryptococcosis during therapy with methotrexate and adalimumab.
PG  - 53-4
AB  - Primary cutaneous infection with Cryptococcus neoformans is uncommon, but can 
      occur following an inoculation injury to the skin. Tumor necrosis factor-alpha 
      (TNF-alpha) is important in the immune response to Cryptococcus, and patients 
      taking inhibitors of TNF-alpha may have increased susceptibility to cryptococcal 
      infection. We report a case of primary cutaneous cryptococcosis in a patient 
      taking adalimumab, methotrexate, and hydroxychloroquine for rheumatoid arthritis.
FAU - Wilson, Morgan L
AU  - Wilson ML
AD  - Geisinger Medical Center, Department of Dermatology, Danville, PA 17822, USA. 
      mlwilson@geisinger.edu
FAU - Sewell, Lindsay D
AU  - Sewell LD
FAU - Mowad, Christen M
AU  - Mowad CM
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Drugs Dermatol
JT  - Journal of drugs in dermatology : JDD
JID - 101160020
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Antibodies, Monoclonal, Humanized)
RN  - 0 (Antifungal Agents)
RN  - 0 (Antirheumatic Agents)
RN  - 4QWG6N8QKH (Hydroxychloroquine)
RN  - 8VZV102JFY (Fluconazole)
RN  - FYS6T7F842 (Adalimumab)
RN  - YL5FZ2Y5U1 (Methotrexate)
SB  - IM
MH  - Adalimumab
MH  - Antibodies, Monoclonal/*therapeutic use
MH  - Antibodies, Monoclonal, Humanized
MH  - Antifungal Agents/therapeutic use
MH  - Antirheumatic Agents/therapeutic use
MH  - Arthritis, Rheumatoid/complications/drug therapy
MH  - Cryptococcosis/complications/*diagnosis/drug therapy
MH  - Cryptococcus neoformans/drug effects/growth & development/isolation & 
      purification
MH  - Dermatomycoses/complications/*diagnosis/drug therapy
MH  - Female
MH  - Finger Injuries/complications/diagnosis/microbiology
MH  - Fluconazole/therapeutic use
MH  - Humans
MH  - Hydroxychloroquine/therapeutic use
MH  - Methotrexate/*therapeutic use
MH  - Middle Aged
EDAT- 2008/02/06 09:00
MHDA- 2008/05/06 09:00
CRDT- 2008/02/06 09:00
PHST- 2008/02/06 09:00 [pubmed]
PHST- 2008/05/06 09:00 [medline]
PHST- 2008/02/06 09:00 [entrez]
PST - ppublish
SO  - J Drugs Dermatol. 2008 Jan;7(1):53-4.