PMID- 18249584
OWN - NLM
STAT- MEDLINE
DCOM- 20080529
LR  - 20220316
IS  - 1471-4906 (Print)
IS  - 1471-4906 (Linking)
VI  - 29
IP  - 3
DP  - 2008 Mar
TI  - HLA-G: from biology to clinical benefits.
PG  - 125-32
LID - 10.1016/j.it.2007.11.005 [doi]
AB  - The relevance of the nonclassical human leukocyte antigen (HLA) class I molecule 
      HLA-G in human physiological and pathological contexts has been the center of 
      intense investigation. In light of the recent advances, we report here the 
      clinical implications of HLA-G as a tolerogenic molecule promoting uterine 
      implantation of the embryo or acceptance of solid allografts while allowing the 
      evasion of tumors or viruses from the immune response. These recent findings are 
      important in terms of clinical benefits at both diagnostic and therapeutic 
      levels.
FAU - Carosella, Edgardo D
AU  - Carosella ED
AD  - Institut Universitaire d'Hematologie, Service de Recherches en 
      Hemato-Immunologie, Hopital Saint-Louis, IUH, 1 75010 Paris, France.
FAU - Moreau, Philippe
AU  - Moreau P
FAU - Lemaoult, Joel
AU  - Lemaoult J
FAU - Rouas-Freiss, Nathalie
AU  - Rouas-Freiss N
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20080204
PL  - England
TA  - Trends Immunol
JT  - Trends in immunology
JID - 100966032
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-G Antigens)
RN  - 0 (Histocompatibility Antigens Class I)
SB  - IM
MH  - Animals
MH  - Embryo Implantation/immunology
MH  - HLA Antigens/*physiology/*therapeutic use
MH  - HLA-G Antigens
MH  - Histocompatibility Antigens Class I/*physiology/*therapeutic use
MH  - Humans
MH  - Transplantation Tolerance/immunology
MH  - Tumor Escape/immunology
RF  - 77
EDAT- 2008/02/06 09:00
MHDA- 2008/05/30 09:00
CRDT- 2008/02/06 09:00
PHST- 2007/10/19 00:00 [received]
PHST- 2007/11/20 00:00 [revised]
PHST- 2007/11/27 00:00 [accepted]
PHST- 2008/02/06 09:00 [pubmed]
PHST- 2008/05/30 09:00 [medline]
PHST- 2008/02/06 09:00 [entrez]
AID - S1471-4906(08)00005-7 [pii]
AID - 10.1016/j.it.2007.11.005 [doi]
PST - ppublish
SO  - Trends Immunol. 2008 Mar;29(3):125-32. doi: 10.1016/j.it.2007.11.005. Epub 2008 
      Feb 4.