PMID- 18250936
OWN - NLM
STAT- MEDLINE
DCOM- 20121002
LR  - 20210915
IS  - 0256-9574 (Print)
VI  - 97
IP  - 11 Pt 3
DP  - 2007 Nov
TI  - Malaria control in South Africa - challenges and successes.
PG  - 1193-7
AB  - Control measures have substantially reduced the historical distribution of 
      malaria in South Africa; the country's population currently at risk for 
      contracting malaria is approximately 4.3 million, predominantly in the northern 
      and eastern border areas. The major strategies for malaria control are vector 
      control through indoor residual spraying, case management, disease surveillance, 
      epidemic preparedness and response, and public awareness. There has been a 
      significant and sustained decrease in malaria case notifications since 2000, as a 
      result of intensive indoor residual spraying including the use of DDT to combat 
      insecticide-resistant Anopheles funestus; the introduction of artemisinin 
      combination therapy; and the Lebombo Spatial Initiative, a cross-border 
      collaboration targeting malaria in eastern Swaziland, southern Mozambique and 
      northern KwaZulu-Natal (KZN). Rapid malaria antigen detection tests are widely 
      used for diagnosis at primary health care level. HIV-malaria co-infected patients 
      who are malaria non-immune are at risk for severe malaria. Renal failure has been 
      identified as a particular complication in this group of patients. Despite 
      successes in malaria control in South Africa, many challenges remain.
FAU - Blumberg, L
AU  - Blumberg L
AD  - National Institute for Communicable Diseases, Johannesburg, South Africa.
FAU - Frean, J
AU  - Frean J
LA  - eng
PT  - Historical Article
PT  - Journal Article
PL  - South Africa
TA  - S Afr Med J
JT  - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
JID - 0404520
RN  - 0 (Anti-Infective Agents)
RN  - 0 (Antimalarials)
RN  - 0 (Artemisinins)
RN  - 886U3H6UFF (Chloroquine)
RN  - 9RMU91N5K2 (artemisinin)
SB  - IM
MH  - Anti-Infective Agents/therapeutic use
MH  - Antimalarials/therapeutic use
MH  - Artemisinins/therapeutic use
MH  - Chloroquine/therapeutic use
MH  - HIV Infections/complications
MH  - History, 19th Century
MH  - History, 20th Century
MH  - Humans
MH  - Malaria/diagnosis/drug therapy/epidemiology/*prevention & control
MH  - Mosquito Control
MH  - South Africa/epidemiology
MH  - Travel
EDAT- 2008/02/06 09:00
MHDA- 2012/10/04 06:00
CRDT- 2008/02/06 09:00
PHST- 2008/02/06 09:00 [pubmed]
PHST- 2012/10/04 06:00 [medline]
PHST- 2008/02/06 09:00 [entrez]
PST - ppublish
SO  - S Afr Med J. 2007 Nov;97(11 Pt 3):1193-7.