PMID- 18253032
OWN - NLM
STAT- MEDLINE
DCOM- 20080221
LR  - 20080206
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Linking)
VI  - 119
IP  - 3-4
DP  - 2007
TI  - Chromosomal localization of the telomeric (TTAGGG)n sequence in eight species of 
      New World Primates (Neotropical Primates, Platyrrhini).
PG  - 221-4
LID - 10.1159/000112064 [doi]
AB  - Chromosomal localization of the telomeric sequence (TTAGGG)(n) in eight New World 
      Primates (Platyrrhini) (Alouatta caraya, Alouatta palliata, Alouatta guariba 
      clamitans, Aotus azarae, Ateles chamek, Cebus nigritus, Cebus paraguayanus, and 
      Saimiri boliviensis) using Fluorescence In Situ Hybridization (FISH) with a 
      peptide nucleic acid (PNA) pantelomeric probe and their possible relationship 
      with the C-banding pattern were analyzed. FISH showed telomeric signals only at 
      the terminal regions of chromosomes from all the species analyzed. Although all 
      of them showed centromeric C+ bands and different size and location of 
      extracentromeric C+ bands, none, except Aotus azarae exhibited (peri)centromeric 
      interstitial telomere-like sequences (ITS). The presence of ITS in Aotus azarae 
      was limited to one pair of submetacentric chromosomes and very likely represents 
      telomeric sequences remaining after a fusion event of ancestral chromosomes 
      during karyotype evolution. Therefore, our data indicate that the distribution of 
      heterochromatin blocks do not correlate with the presence of ITS. However, we 
      cannot rule out the possibility that simple ITS arrays with a few copies of the 
      (TTAGGG)(n) sequence, not detectable by conventional FISH, might play a role in 
      the karyotypic evolution of Ceboidea. Further FISH and molecular studies will be 
      needed to confirm this hypothesis.
CI  - Copyright (c) 2008 S. Karger AG, Basel.
FAU - Mudry, M D
AU  - Mudry MD
AD  - Grupo de Investigacion en Biologia Evolutiva (GIBE), Dpto. Ecologia, Genetica y 
      Evolucion, FCEyN, Universidad de Buenos Aires, Ciudad Universitaria, Ciudad 
      Autonoma de Buenos Aires, Argentina. martamudry@yahoo.com.ar
FAU - Nieves, M
AU  - Nieves M
FAU - Bolzan, A D
AU  - Bolzan AD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080201
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Chromosomes, Mammalian/*genetics
MH  - Female
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Platyrrhini/*genetics
MH  - Telomere/*genetics
EDAT- 2008/02/07 09:00
MHDA- 2008/02/22 09:00
CRDT- 2008/02/07 09:00
PHST- 2007/10/15 00:00 [accepted]
PHST- 2008/02/07 09:00 [pubmed]
PHST- 2008/02/22 09:00 [medline]
PHST- 2008/02/07 09:00 [entrez]
AID - 000112064 [pii]
AID - 10.1159/000112064 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2007;119(3-4):221-4. doi: 10.1159/000112064. Epub 2008 Feb 
      1.