PMID- 18255364
OWN - NLM
STAT- MEDLINE
DCOM- 20080501
LR  - 20181201
IS  - 1570-0232 (Print)
IS  - 1570-0232 (Linking)
VI  - 863
IP  - 1
DP  - 2008 Feb 15
TI  - Preconcentration of pharmaceuticals residues in sediment samples using microwave 
      assisted micellar extraction coupled with solid phase extraction and their 
      determination by HPLC-UV.
PG  - 150-7
LID - 10.1016/j.jchromb.2008.01.026 [doi]
AB  - An analytical method combining microwave assisted micellar extraction (MAME) and 
      solid phase extraction (SPE) has been developed to extract and preconcentrate a 
      selected group of eight pharmaceutical compounds in sediment samples prior to 
      their determination using liquid chromatography with an UV-DAD detector. A 
      non-ionic surfactant, Polyoxyethylene 10 lauryl ether (POLE) was used for the 
      MAME extraction and the different parameters for the optimization process were 
      studied. Then, SPE was used to clean-up and preconcentrate the target analytes in 
      the extract, prior to their determination using HPLC-UV. The method was applied 
      to the determination of the selected pharmaceuticals compounds in several kinds 
      of sediment samples with different characteristics. Relative recoveries for 
      spiked sediment samples were over 70% and relative standard deviations (RSDs) 
      were under 11% for all recoveries tested. Detection limits between 4 and 
      167ngg(-1) were obtained. The method was validated using Soxhlet extraction 
      procedure.
FAU - Cueva-Mestanza, R
AU  - Cueva-Mestanza R
AD  - Department of Chemistry, University of Las Palmas de Gran Canaria, 35017 Las 
      Palmas de Gran Canaria, Spain.
FAU - Sosa-Ferrera, Z
AU  - Sosa-Ferrera Z
FAU - Torres-Padron, M E
AU  - Torres-Padron ME
FAU - Santana-Rodriguez, J J
AU  - Santana-Rodriguez JJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080120
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 0 (Indicators and Reagents)
RN  - 0 (Micelles)
RN  - 0 (Soil)
RN  - 0 (Soil Pollutants)
RN  - 0AWH8BFG9A (Polidocanol)
RN  - 3WJQ0SDW1A (Polyethylene Glycols)
SB  - IM
MH  - Calibration
MH  - Chemical Phenomena
MH  - Chemistry, Physical
MH  - Chromatography, High Pressure Liquid
MH  - Drug Residues/*analysis
MH  - Geologic Sediments/*analysis
MH  - Indicators and Reagents
MH  - Micelles
MH  - Microwaves
MH  - Polidocanol
MH  - Polyethylene Glycols
MH  - Quality Control
MH  - Soil/analysis
MH  - Soil Pollutants/*analysis
MH  - Solid Phase Extraction
MH  - Spain
MH  - Spectrophotometry, Ultraviolet
EDAT- 2008/02/08 09:00
MHDA- 2008/05/02 09:00
CRDT- 2008/02/08 09:00
PHST- 2007/09/13 00:00 [received]
PHST- 2007/12/18 00:00 [revised]
PHST- 2008/01/15 00:00 [accepted]
PHST- 2008/02/08 09:00 [pubmed]
PHST- 2008/05/02 09:00 [medline]
PHST- 2008/02/08 09:00 [entrez]
AID - S1570-0232(08)00063-9 [pii]
AID - 10.1016/j.jchromb.2008.01.026 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Feb 15;863(1):150-7. doi: 
      10.1016/j.jchromb.2008.01.026. Epub 2008 Jan 20.