PMID- 18266223
OWN - NLM
STAT- MEDLINE
DCOM- 20080731
LR  - 20201226
IS  - 1545-5017 (Electronic)
IS  - 1545-5009 (Linking)
VI  - 51
IP  - 1
DP  - 2008 Jul
TI  - Allogeneic stem cell transplantation in a patient with relapsed Ewing sarcoma.
PG  - 142-4
LID - 10.1002/pbc.21503 [doi]
AB  - Ewing sarcoma (ES) can express tumor antigens which can be recognized by T cells, 
      making allogeneic stem cell transplant (SCT) a potential option for those 
      patients with refractory disease. A 6-year old with multifocal ES developed a 
      recurrence of pulmonary metastases and underwent an allogeneic bone marrow 
      transplant from her human leukocyte antigen (HLA) 10/10 matched mother. During a 
      taper of her immunosuppression, she developed grade 1 skin and oral graft versus 
      host disease (GVHD). CT scans performed 9 months post-transplant revealed a 
      marked decrease in the size of her pulmonary lesions compared to scans 2 months 
      post-transplant. This case highlights the possibility of treating patients with 
      refractory metastatic ES with allogeneic SCT.
CI  - (c) 2008 Wiley-Liss, Inc.
FAU - Lucas, Kenneth G
AU  - Lucas KG
AD  - Division of Pediatric Hematology-Oncology, Stem Cell Transplantation Program, 
      Penn State Children's Hospital, Hershey, Pennsylvania, USA. klucas@psu.edu
FAU - Schwartz, Cindy
AU  - Schwartz C
FAU - Kaplan, Joel
AU  - Kaplan J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Pediatr Blood Cancer
JT  - Pediatric blood & cancer
JID - 101186624
SB  - IM
MH  - Child
MH  - Female
MH  - Graft vs Host Disease/pathology
MH  - Hematopoietic Stem Cell Transplantation/*methods
MH  - Humans
MH  - Lung Neoplasms/secondary
MH  - Sarcoma, Ewing/pathology/*therapy
MH  - Transplantation, Homologous
MH  - Treatment Outcome
EDAT- 2008/02/13 09:00
MHDA- 2008/08/01 09:00
CRDT- 2008/02/13 09:00
PHST- 2008/02/13 09:00 [pubmed]
PHST- 2008/08/01 09:00 [medline]
PHST- 2008/02/13 09:00 [entrez]
AID - 10.1002/pbc.21503 [doi]
PST - ppublish
SO  - Pediatr Blood Cancer. 2008 Jul;51(1):142-4. doi: 10.1002/pbc.21503.