PMID- 18268544 OWN - NLM STAT- MEDLINE DCOM- 20080225 LR - 20131121 IS - 1476-5373 (Electronic) IS - 0007-0610 (Linking) VI - 204 IP - 2 DP - 2008 Jan 26 TI - Ecstasy (MDMA) and oral health. PG - 77-81 LID - 10.1038/bdj.2008.4 [doi] AB - 3,4-methylenedioxymethamphetamine (MDMA), more commonly known as 'ecstasy' or XTC, is frequently used by young adults in the major cities. Therefore, it is likely that dentists might be confronted with individuals who use ecstasy. This review describes systemic and oral effects of ecstasy. Life-threatening complications include hyperthermia, hyponatraemia and liver failure. In addition, psychotic episodes, depression, panic disorders and impulsive behaviour have been reported. Oral effects include xerostomia, bruxism, and an increased risk of developing dental erosion. Mucosal changes have also been reported. Recent use of ecstasy may interfere with dental treatment. Finally, the potential use of saliva for non-invasive detection of ecstasy is discussed. FAU - Brand, H S AU - Brand HS AD - Department of Dental Basic Sciences, Section of Oral Biochemistry, Centre for Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands. hs.brand@vumc.nl FAU - Dun, S N AU - Dun SN FAU - Nieuw Amerongen, A V AU - Nieuw Amerongen AV LA - eng PT - Journal Article PT - Review PL - England TA - Br Dent J JT - British dental journal JID - 7513219 RN - 0 (Hallucinogens) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM CIN - Br Dent J. 2008 Mar 22;204(6):282-3. PMID: 18356857 MH - Adult MH - Animals MH - Bruxism/chemically induced/complications MH - *Dental Care for Chronically Ill MH - Hallucinogens/*adverse effects/chemistry MH - Humans MH - N-Methyl-3,4-methylenedioxyamphetamine/*adverse effects/chemistry MH - Oral Ulcer/chemically induced MH - Saliva/chemistry MH - Substance-Related Disorders/*etiology MH - Tooth Abrasion/etiology MH - Tooth Erosion/chemically induced MH - Xerostomia/chemically induced RF - 46 EDAT- 2008/02/13 09:00 MHDA- 2008/02/26 09:00 CRDT- 2008/02/13 09:00 PHST- 2007/11/01 00:00 [accepted] PHST- 2008/02/13 09:00 [pubmed] PHST- 2008/02/26 09:00 [medline] PHST- 2008/02/13 09:00 [entrez] AID - bdj.2008.4 [pii] AID - 10.1038/bdj.2008.4 [doi] PST - ppublish SO - Br Dent J. 2008 Jan 26;204(2):77-81. doi: 10.1038/bdj.2008.4.