PMID- 18272671
OWN - NLM
STAT- MEDLINE
DCOM- 20081215
LR  - 20220321
IS  - 1468-2060 (Electronic)
IS  - 0003-4967 (Linking)
VI  - 67
IP  - 12
DP  - 2008 Dec
TI  - Reactive arthritis following culture-confirmed infections with bacterial enteric 
      pathogens in Minnesota and Oregon: a population-based study.
PG  - 1689-96
LID - 10.1136/ard.2007.083451 [doi]
AB  - OBJECTIVE: To describe the epidemiology and clinical spectrum of reactive 
      arthritis (ReA) following culture-confirmed infection with bacterial enteric 
      pathogens in a population-based study in the USA. METHODS: We conducted telephone 
      interviews of persons age>1 year with culture confirmed Campylobacter, 
      Escherichia coli O157, Salmonella, Shigella and Yersinia infections reported to 
      FoodNet (http://www.cdc.gov/FoodNet/) in Minnesota, USA and Oregon, USA between 
      2002 and 2004. SUBJECTS: with new onset joint pain, joint swelling, back pain, 
      heel pain and morning stiffness lasting >or=3 days within 8 weeks of culture 
      (possible ReA) were invited to complete a detailed questionnaire and physical 
      examination. RESULTS: A total of 6379 culture-confirmed infections were reported; 
      70% completed screening interviews. Of these, 575 (13%) developed possible ReA; 
      incidence was highest following Campylobacter (2.1/100,000) and Salmonella 
      (1.4/100,000) infections. Risk was greater for females (relative risk (RR) 1.5, 
      95% CI, 1.3 to 1.7), adults (RR 2.5, 95% CI, 2.0 to 3.1) and subjects with severe 
      acute illness (eg, fever, chills, headache, persistent diarrhoea). Risk was not 
      associated with antibiotic use or human leukocyte antigen (HLA)-B27. A total of 
      54 (66%) of 82 subjects examined had confirmed ReA. Enthesitis was the most 
      frequent finding; arthritis was less common. The estimated incidence of ReA 
      following culture-confirmed Campylobacter, E coli O157, Salmonella, Shigella and 
      Yersinia infections in Oregon was 0.6-3.1 cases/100,000. CONCLUSIONS: This is the 
      first population-based study of ReA following infections due to bacterial enteric 
      pathogens in the USA. These data will help determine the burden of illness due to 
      these pathogens and inform clinicians about potential sequelae of these 
      infections.
FAU - Townes, J M
AU  - Townes JM
AD  - Oregon Health and Science University, Mailcode L457, 3181 SW Sam Jackson Park 
      Road, Portland, Oregon 97239-3098, USA. townesj@ohsu.edu
FAU - Deodhar, A A
AU  - Deodhar AA
FAU - Laine, E S
AU  - Laine ES
FAU - Smith, K
AU  - Smith K
FAU - Krug, H E
AU  - Krug HE
FAU - Barkhuizen, A
AU  - Barkhuizen A
FAU - Thompson, M E
AU  - Thompson ME
FAU - Cieslak, P R
AU  - Cieslak PR
FAU - Sobel, J
AU  - Sobel J
LA  - eng
GR  - M01 RR000334/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
DEP - 20080213
PL  - England
TA  - Ann Rheum Dis
JT  - Annals of the rheumatic diseases
JID - 0372355
SB  - IM
MH  - Acute Disease
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Arthritis, Reactive/*epidemiology/microbiology
MH  - Campylobacter Infections/epidemiology
MH  - Child
MH  - Child, Preschool
MH  - Enterobacteriaceae Infections/*epidemiology
MH  - Epidemiologic Methods
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Minnesota/epidemiology
MH  - Oregon/epidemiology
MH  - Physical Examination/methods
MH  - Prohibitins
MH  - Salmonella Infections/epidemiology
MH  - Sex Distribution
MH  - Young Adult
EDAT- 2008/02/15 09:00
MHDA- 2008/12/17 09:00
CRDT- 2008/02/15 09:00
PHST- 2008/02/15 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2008/02/15 09:00 [entrez]
AID - ard.2007.083451 [pii]
AID - 10.1136/ard.2007.083451 [doi]
PST - ppublish
SO  - Ann Rheum Dis. 2008 Dec;67(12):1689-96. doi: 10.1136/ard.2007.083451. Epub 2008 
      Feb 13.