PMID- 18282301
OWN - NLM
STAT- MEDLINE
DCOM- 20080423
LR  - 20230331
IS  - 1471-2105 (Electronic)
IS  - 1471-2105 (Linking)
VI  - 9
DP  - 2008 Feb 19
TI  - Automated simultaneous analysis phylogenetics (ASAP): an enabling tool for 
      phlyogenomics.
PG  - 103
LID - 10.1186/1471-2105-9-103 [doi]
AB  - BACKGROUND: The availability of sequences from whole genomes to reconstruct the 
      tree of life has the potential to enable the development of phylogenomic 
      hypotheses in ways that have not been before possible. A significant bottleneck 
      in the analysis of genomic-scale views of the tree of life is the time required 
      for manual curation of genomic data into multi-gene phylogenetic matrices. 
      RESULTS: To keep pace with the exponentially growing volume of molecular data in 
      the genomic era, we have developed an automated technique, ASAP (Automated 
      Simultaneous Analysis Phylogenetics), to assemble these multigene/multi species 
      matrices and to evaluate the significance of individual genes within the context 
      of a given phylogenetic hypothesis. CONCLUSION: Applications of ASAP may enable 
      scientists to re-evaluate species relationships and to develop new phylogenomic 
      hypotheses based on genome-scale data.
FAU - Sarkar, Indra Neil
AU  - Sarkar IN
AD  - MBLWHOI Library, Marine Biological Laboratory, Woods Hole, MA, USA. 
      sarkar@mbl.edu
FAU - Egan, Mary G
AU  - Egan MG
FAU - Coruzzi, Gloria
AU  - Coruzzi G
FAU - Lee, Ernest K
AU  - Lee EK
FAU - DeSalle, Rob
AU  - DeSalle R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20080219
PL  - England
TA  - BMC Bioinformatics
JT  - BMC bioinformatics
JID - 100965194
SB  - IM
MH  - *Algorithms
MH  - Base Sequence
MH  - Chromosome Mapping/*methods
MH  - *Evolution, Molecular
MH  - Molecular Sequence Data
MH  - *Phylogeny
MH  - Sequence Alignment/*methods
MH  - Sequence Analysis, DNA/*methods
MH  - *Software
PMC - PMC2270260
EDAT- 2008/02/20 09:00
MHDA- 2008/04/24 09:00
PMCR- 2008/02/19
CRDT- 2008/02/20 09:00
PHST- 2007/10/31 00:00 [received]
PHST- 2008/02/19 00:00 [accepted]
PHST- 2008/02/20 09:00 [pubmed]
PHST- 2008/04/24 09:00 [medline]
PHST- 2008/02/20 09:00 [entrez]
PHST- 2008/02/19 00:00 [pmc-release]
AID - 1471-2105-9-103 [pii]
AID - 10.1186/1471-2105-9-103 [doi]
PST - epublish
SO  - BMC Bioinformatics. 2008 Feb 19;9:103. doi: 10.1186/1471-2105-9-103.