PMID- 1828443
OWN - NLM
STAT- MEDLINE
DCOM- 19910718
LR  - 20190828
IS  - 0020-711X (Print)
IS  - 0020-711X (Linking)
VI  - 23
IP  - 3
DP  - 1991
TI  - The effects of diet on the maximal activities of glutaminase, citrate synthase, 
      hexokinase, 6-phosphofructokinase and lactate dehydrogenase in the skin of haired 
      and hairless mice of various ages.
PG  - 365-9
AB  - 1. The maximal activities of hexokinase (HK), 6-phosphofructokinase (PFK), 
      lactate dehydrogenase (LDH), citrate synthase (CS) and glutaminase (GLU) which 
      provide a quantitative indices of flux through several important pathways have 
      been measured in the skin of haired Balb/c and hairless Balb/c (nu/nu) mice under 
      normal and dietary stress. 2. The skin of old haired mice exhibited higher PFK 
      and LDH activities with lower HK, CS and GLU activities. All activities of 
      enzymes associated with energy metabolism in the skin of old hairless mice were 
      higher than those in the skin of haired mice. 3. HK, LDH, CS and GLU activities 
      were maintained at normal levels in the skin of haired mice when these mice were 
      fed diets deficient in energy or protein components (HPLE, LPNE). These enzymes 
      however were severely suppressed when mice were fed a diet deficient in both 
      energy and protein components (LPLE). Recovery of activities of these enzymes to 
      the control level was observed when mice were refed with the normal diet for a 
      week.
FAU - Nguyen, T D
AU  - Nguyen TD
AD  - Department of Microbiology, University of Western Australia, Queen Elizabeth II 
      Medical Centre, Nedlands.
FAU - Keast, D
AU  - Keast D
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Int J Biochem
JT  - The International journal of biochemistry
JID - 0250365
RN  - 0 (Dietary Proteins)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.3.3.1 (Citrate (si)-Synthase)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.1.11 (Phosphofructokinase-1)
RN  - EC 3.5.1.2 (Glutaminase)
SB  - IM
MH  - Aging/metabolism
MH  - Animals
MH  - Citrate (si)-Synthase/*metabolism
MH  - *Diet
MH  - Dietary Proteins/administration & dosage/pharmacology
MH  - Energy Intake
MH  - Energy Metabolism
MH  - Glutaminase/*metabolism
MH  - Hexokinase/*metabolism
MH  - L-Lactate Dehydrogenase/*metabolism
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Mice, Nude
MH  - Phosphofructokinase-1/*metabolism
MH  - Skin/*enzymology
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
AID - 10.1016/0020-711x(91)90120-c [doi]
PST - ppublish
SO  - Int J Biochem. 1991;23(3):365-9. doi: 10.1016/0020-711x(91)90120-c.