PMID- 18286450
OWN - NLM
STAT- MEDLINE
DCOM- 20080429
LR  - 20191027
IS  - 0391-3988 (Print)
IS  - 0391-3988 (Linking)
VI  - 31
IP  - 1
DP  - 2008 Jan
TI  - Acid-base disturbances in the intensive care unit: current issues and the use of 
      continuous renal replacement therapy as a customized treatment tool.
PG  - 6-14
AB  - Continuous renal replacement therapies (CRRT) are often used to manage complex 
      acid-base problems in critically ill patients. These techniques allow a constant 
      manipulation of the plasma composition. Several technical factors from CRRT 
      influence the acid-base status; namely, the effluent rate, the operational 
      characteristics of the technique, the content of the solutions and the metabolic 
      rate of the buffer. This article reviews the common acid base disorders occurring 
      in the intensive care unit, using both the anion gap and the strong ion gap 
      approaches, and describes the influence of CRRT on acid-base physiology. The use 
      of CRRT as a customized therapy for acid-base disorders is discussed, allowing an 
      integration of both physiological and technical concepts.
FAU - Bouchard, J
AU  - Bouchard J
AD  - Division of Nephrology, Department of Medicine, University of California San 
      Diego, California - USA.
FAU - Mehta, R L
AU  - Mehta RL
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Int J Artif Organs
JT  - The International journal of artificial organs
JID - 7802649
RN  - 0 (Dialysis Solutions)
SB  - IM
MH  - Acid-Base Equilibrium/drug effects/*physiology
MH  - Acidosis/drug therapy/physiopathology
MH  - Acute Kidney Injury/*therapy
MH  - Alkalosis/drug therapy/physiopathology
MH  - Dialysis Solutions/chemistry/pharmacology
MH  - Hemofiltration/*methods
MH  - Humans
MH  - Intensive Care Units
MH  - Kidney/injuries
RF  - 36
EDAT- 2008/02/21 09:00
MHDA- 2008/04/30 09:00
CRDT- 2008/02/21 09:00
PHST- 2008/02/21 09:00 [pubmed]
PHST- 2008/04/30 09:00 [medline]
PHST- 2008/02/21 09:00 [entrez]
AID - 10.1177/039139880803100103 [doi]
PST - ppublish
SO  - Int J Artif Organs. 2008 Jan;31(1):6-14. doi: 10.1177/039139880803100103.