PMID- 18291245
OWN - NLM
STAT- MEDLINE
DCOM- 20080624
LR  - 20080222
IS  - 0022-3999 (Print)
IS  - 0022-3999 (Linking)
VI  - 64
IP  - 3
DP  - 2008 Mar
TI  - Panic disorder in patients with chronic heart failure.
PG  - 299-303
LID - 10.1016/j.jpsychores.2007.09.002 [doi]
AB  - OBJECTIVE: Our objective was to assess the prevalence of panic disorder, its 
      influence on quality of life (QoL), and the presence of further anxiety and 
      depressive comorbid disorders in outpatients with chronic heart failure (CHF). 
      METHODS: In a cross-sectional study, anxiety and depressive disorders were 
      diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, 
      Fourth Edition diagnostic criteria in patients with CHF who were aged > or =18 
      years and had New York Heart Association (NYHA) Functional Classes I-IV, using 
      the Patient Health Questionnaire. Health-related QoL was evaluated using the 
      Short-Form 36 Health Survey (SF-36). RESULTS: Of the 258 participating patients, 
      24 (9.3%) fulfilled diagnostic criteria for panic disorder. Seven of these 
      (29.2%) were diagnosed with comorbid anxiety disorders, 11 (47.3%) were diagnosed 
      with comorbid depressive disorder, and 5 (20.8%) were diagnosed with other 
      anxiety disorders and any depressive disorder. Female gender [odds ratio 
      (OR)=3.1; 95% confidence interval (95% CI)=1.2-7.8; P=.02] and a lower level of 
      education (OR=0.3; 95% CI=0.1-0.9; P=.04) were associated with the presence of 
      panic disorder. In patients with panic disorder, QoL was significantly more 
      restricted on all subscales of the SF-36 as compared to those without panic 
      disorder, even when age, gender, and NYHA functional class were controlled for 
      (P=.05 to <.01). CONCLUSION: Approximately 1 of 10 patients with CHF suffers from 
      panic disorder, many of whom also have additional anxiety or depressive comorbid 
      disorders. Female gender and a low level of education are positively associated 
      with the presence of panic disorder. QoL is severely limited by the presence of 
      panic disorder. Diagnosis of mental disorders and treatment offers for affected 
      patients should be available in patient care.
FAU - Muller-Tasch, Thomas
AU  - Muller-Tasch T
AD  - Department of Psychosomatic and General Internal Medicine, University of 
      Heidelberg, Heidelberg, Germany. Thomas.Mueller-Tasch@med.uni-heidelberg.de
FAU - Frankenstein, Lutz
AU  - Frankenstein L
FAU - Holzapfel, Nicole
AU  - Holzapfel N
FAU - Schellberg, Dieter
AU  - Schellberg D
FAU - Lowe, Bernd
AU  - Lowe B
FAU - Nelles, Manfred
AU  - Nelles M
FAU - Zugck, Christian
AU  - Zugck C
FAU - Katus, Hugo
AU  - Katus H
FAU - Rauch, Bernhard
AU  - Rauch B
FAU - Haass, Markus
AU  - Haass M
FAU - Junger, Jana
AU  - Junger J
FAU - Remppis, Andrew
AU  - Remppis A
FAU - Herzog, Wolfgang
AU  - Herzog W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Psychosom Res
JT  - Journal of psychosomatic research
JID - 0376333
SB  - IM
MH  - Chronic Disease
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Female
MH  - Heart Failure/*epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Panic Disorder/diagnosis/*epidemiology
MH  - Prevalence
MH  - Quality of Life/psychology
EDAT- 2008/02/23 09:00
MHDA- 2008/06/25 09:00
CRDT- 2008/02/23 09:00
PHST- 2007/07/09 00:00 [received]
PHST- 2007/09/10 00:00 [revised]
PHST- 2007/09/11 00:00 [accepted]
PHST- 2008/02/23 09:00 [pubmed]
PHST- 2008/06/25 09:00 [medline]
PHST- 2008/02/23 09:00 [entrez]
AID - S0022-3999(07)00360-1 [pii]
AID - 10.1016/j.jpsychores.2007.09.002 [doi]
PST - ppublish
SO  - J Psychosom Res. 2008 Mar;64(3):299-303. doi: 10.1016/j.jpsychores.2007.09.002.