PMID- 18295364
OWN - NLM
STAT- MEDLINE
DCOM- 20080617
LR  - 20191210
IS  - 0167-8760 (Print)
IS  - 0167-8760 (Linking)
VI  - 68
IP  - 1
DP  - 2008 Apr
TI  - Gender differences in lateralization of mismatch negativity in dichotic listening 
      tasks.
PG  - 41-50
LID - 10.1016/j.ijpsycho.2008.01.006 [doi]
AB  - OBJECTIVE: With the aim of investigating gender differences in the functional 
      lateralization subserving preattentive processing of language stimuli, we 
      compared auditory mismatch negativities (MMNs) using dichotic listening tasks. 
      METHODS: Forty-four healthy volunteers, including 23 males and 21 females, 
      participated in the study. MMNs generated by pure-tone and phonetic stimuli were 
      compared, to check for the existence of language-specific gender differences in 
      lateralization. Both EEG amplitude and scalp current density (SCD) data were 
      analyzed. RESULTS: With phonetic MMNs, EEG findings revealed significantly larger 
      amplitude in females than males, especially in the right hemisphere, while SCD 
      findings revealed left hemisphere dominance and contralateral dominance in males 
      alone. With pure-tone MMNs, no significant gender differences in hemispheric 
      lateralization appeared in either EEG or SCD findings. CONCLUSION: While males 
      exhibited left-lateralized activation with phonetic MMNs, females exhibited more 
      bilateral activity. Further, the contralateral dominance of the SCD distribution 
      associated with the ear receiving deviant stimuli in males indicated that 
      ipsilateral input as well as interhemispheric transfer across the corpus callosum 
      to the ipsilateral side was more suppressed in males than in females. 
      SIGNIFICANCE: The findings of the present study suggest that functional 
      lateralization subserving preattentive detection of phonetic change differs 
      between the genders. These results underscore the significance of considering the 
      gender differences in the study of MMN, especially when phonetic stimulus is 
      adopted. Moreover, they support the view of Voyer and Flight [Voyer, D., Flight, 
      J., 2001. Gender differences in laterality on a dichotic task: the influence of 
      report strategies. Cortex 37, 345-362.] in that the gender difference in 
      hemispheric lateralization of language function is observed in a 
      well-managed-attention condition, which fits the condition adopted in the MMN 
      measurement; subjects are required to focus attention to a distraction task and 
      thereby ignore the phonetic stimuli that elicit MMN.
FAU - Ikezawa, Satoru
AU  - Ikezawa S
AD  - Department of Psychiatry, Showa University School of Medicine, Shinagawa-ku, 
      Tokyo 142-8666, Japan. satoruikezawa@grape.med.tottori-u.ac.jp
FAU - Nakagome, Kazuyuki
AU  - Nakagome K
FAU - Mimura, Masaru
AU  - Mimura M
FAU - Shinoda, Junko
AU  - Shinoda J
FAU - Itoh, Kenji
AU  - Itoh K
FAU - Homma, Ikuo
AU  - Homma I
FAU - Kamijima, Kunitoshi
AU  - Kamijima K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080126
PL  - Netherlands
TA  - Int J Psychophysiol
JT  - International journal of psychophysiology : official journal of the International 
      Organization of Psychophysiology
JID - 8406214
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Attention/*physiology
MH  - Auditory Perception/*physiology
MH  - Cerebral Cortex/physiology
MH  - *Contingent Negative Variation
MH  - Dichotic Listening Tests
MH  - Discrimination, Psychological/*physiology
MH  - Female
MH  - Field Dependence-Independence
MH  - Functional Laterality/*physiology
MH  - Humans
MH  - Male
MH  - Phonetics
MH  - Reference Values
MH  - Sex Factors
EDAT- 2008/02/26 09:00
MHDA- 2008/06/18 09:00
CRDT- 2008/02/26 09:00
PHST- 2007/07/18 00:00 [received]
PHST- 2007/12/12 00:00 [revised]
PHST- 2008/01/08 00:00 [accepted]
PHST- 2008/02/26 09:00 [pubmed]
PHST- 2008/06/18 09:00 [medline]
PHST- 2008/02/26 09:00 [entrez]
AID - S0167-8760(08)00008-1 [pii]
AID - 10.1016/j.ijpsycho.2008.01.006 [doi]
PST - ppublish
SO  - Int J Psychophysiol. 2008 Apr;68(1):41-50. doi: 10.1016/j.ijpsycho.2008.01.006. 
      Epub 2008 Jan 26.