PMID- 18296330
OWN - NLM
STAT- MEDLINE
DCOM- 20080702
LR  - 20220408
IS  - 0964-7058 (Print)
IS  - 0964-7058 (Linking)
VI  - 17 Suppl 1
DP  - 2008
TI  - Childhood obesity in Asian Indians: a burgeoning cause of insulin resistance, 
      diabetes and sub-clinical inflammation.
PG  - 172-5
AB  - Recent data indicate a rise in obesity both in children and adolescents in 
      developing countries. The overall prevalence of overweight/obesity in urban 
      children in New Delhi has shown an increase from 16% in 2002 to about 24% in 
      2006-2007. Our recent data show that the prevalence among adolescent children was 
      29% in private schools and 11.3% in government funded schools. While India 
      already has highest number of patients with type 2 diabetes mellitus (T2DM) 
      globally, rapid rise of obesity in children is the prime reason for increasing 
      insulin resistance, the metabolic syndrome, dyslipidemia, polycystic ovarian 
      syndrome and raised levels of C-reactive protein. Excess body fat, thick truncal 
      subcutaneous fat, and abdominal adiposity are important predisposing factors for 
      development of insulin resistance in Asian Indian children. As compared to other 
      ethnic groups, children with ancestral origin in South Asia manifest adiposity, 
      insulin resistance and metabolic perturbations earlier in life and these 
      derangements are of higher magnitude than white Caucasian children. Since the 
      metabolic syndrome and obesity track into adulthood, these clinical entities need 
      to be recognized early for effective prevention of T2DM and coronary heart 
      disease. Therapeutic lifestyle changes, maintenance of high levels of physical 
      activity and normal weight are most important prevention strategies. Both 
      high-risk surveillance and cost-effective population intervention programs are 
      urgently needed. In this context, we have launched one of the largest program 
      ("MARG", The Path) to curb childhood obesity in India.
FAU - Bhardwaj, Swati
AU  - Bhardwaj S
AD  - Department of Diabetes and Metabolic Diseases Fortis Flt. Lt Rajan Dhall 
      Hospital, New Dheli, India. anoopmisra@metabolicresearchindia.com
FAU - Misra, Anoop
AU  - Misra A
FAU - Khurana, Lokesh
AU  - Khurana L
FAU - Gulati, Seema
AU  - Gulati S
FAU - Shah, Priyali
AU  - Shah P
FAU - Vikram, Naval K
AU  - Vikram NK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - China
TA  - Asia Pac J Clin Nutr
JT  - Asia Pacific journal of clinical nutrition
JID - 9440304
SB  - IM
MH  - Adolescent
MH  - Asia/ethnology
MH  - Child
MH  - Diabetes Mellitus, Type 2/*epidemiology/etiology/prevention & control
MH  - Female
MH  - Humans
MH  - India/epidemiology
MH  - Inflammation
MH  - *Insulin Resistance
MH  - Life Style
MH  - Male
MH  - Obesity/complications/*epidemiology/prevention & control
MH  - Overweight/complications/*epidemiology/prevention & control
MH  - Prevalence
MH  - Sentinel Surveillance
RF  - 15
EDAT- 2008/05/28 09:00
MHDA- 2008/07/03 09:00
CRDT- 2008/05/28 09:00
PHST- 2008/05/28 09:00 [pubmed]
PHST- 2008/07/03 09:00 [medline]
PHST- 2008/05/28 09:00 [entrez]
PST - ppublish
SO  - Asia Pac J Clin Nutr. 2008;17 Suppl 1:172-5.