PMID- 1829691
OWN - NLM
STAT- MEDLINE
DCOM- 19910814
LR  - 20190828
IS  - 0020-711X (Print)
IS  - 0020-711X (Linking)
VI  - 23
IP  - 5-6
DP  - 1991
TI  - Maximal activities of glutaminase, citrate synthase, hexokinase, 
      6-phosphofructokinase and lactate dehydrogenase in skin of immune-competent 
      Balb/c and immune-deficient Balb/c (nu/nu) mice during wound healing.
PG  - 589-93
AB  - 1. The maximal activities of hexokinase (HK), 6-phosphofructokinase (PFK), 
      lactate dehydrogenase, citrate synthase (CS) and glutaminase (GLU) which provide 
      quantitative and qualitative indices of flux through several important metabolic 
      pathways have been examined in the wounded skin of haired immune competent Balb/c 
      mice and hairless immune deficient Balb/c (nu/nu) mice of various ages during the 
      first ten days of wound healing. 2. The potential for glucose utilization and for 
      aerobic metabolism as suggested by the maximal activities of HK, PFK, CS, were 
      raised in the skin of Balb/c mice of various ages on all post wounding days. 
      Increases in the maximal activity of GLU was observed only in the skin of 6 and 
      10 weeks old Balb/c mice during wound healing. 3. There was no evidence of a 
      contribution to the maximal activity of GLU by infiltrating cells of the immune 
      system to the wound site in the skin of either haired or hairless mice.
FAU - Nguyen, D T
AU  - Nguyen DT
AD  - Department of Microbiology, University of Western Australia, Queens Elizabeth II 
      Medical Centre, Nedlands.
FAU - Keast, D
AU  - Keast D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Int J Biochem
JT  - The International journal of biochemistry
JID - 0250365
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.3.3.1 (Citrate (si)-Synthase)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 2.7.1.11 (Phosphofructokinase-1)
RN  - EC 3.5.1.2 (Glutaminase)
SB  - IM
MH  - Aging/immunology
MH  - Animals
MH  - Citrate (si)-Synthase/metabolism
MH  - Glutaminase/metabolism
MH  - Hexokinase/metabolism
MH  - *Immunocompetence
MH  - L-Lactate Dehydrogenase/metabolism
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Mice, Nude
MH  - Phosphofructokinase-1/metabolism
MH  - Skin/*enzymology/immunology
MH  - Wound Healing/*immunology
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
AID - 10.1016/0020-711x(87)90053-x [doi]
PST - ppublish
SO  - Int J Biochem. 1991;23(5-6):589-93. doi: 10.1016/0020-711x(87)90053-x.