PMID- 18297852 OWN - NLM STAT- MEDLINE DCOM- 20080715 LR - 20150514 IS - 0002-5151 (Print) IS - 0002-5151 (Linking) VI - 54 IP - 4 DP - 2007 Jul-Aug TI - [Allergic disease with IgE hypersynthesis. Proposal of a new denomination for an allergic disease confused with immunodeficiency]. PG - 123-33 AB - Within the variety of diseases in which there is an excessive production of immunoglobulin E (IgE), clinicians have the dilemma to establish a differential diagnosis between allergy, immunodeficiency and even autoimmunity. In the present study the clinical manifestations of allergic patients who presented very high levels of IgE and who were taken care of in the Allergy Service of the National Institute of Pediatrics and did not show criteria to be identified as carriers of some non-atopic immunological disease (eg. Hyper-IgE syndrome), are described. In addition, the regulation and synthesis of IgE is presented. The authors propose that the presence of an allergic entity with or without skin manifestations without any history of recurrent infections or cutaneous abscesses, should be named allergic disease with hypersynthesis of IgE, in which the levels of IgE are greater than 2,000 UI/mL. FAU - Lopez Perez, Gerardo AU - Lopez Perez G AD - Servicio de alergia, Instituto Nacional de Pediatria, Mexico, DF. apiger@prodigy.net.mx FAU - Garcia-Pavon Osorio, Susana AU - Garcia-Pavon Osorio S FAU - Morales Vasquez, Adriana AU - Morales Vasquez A FAU - Yamazaki Nakashimada, Marco Antonio AU - Yamazaki Nakashimada MA LA - spa PT - English Abstract PT - Journal Article PT - Review TT - Enfermedad alergica con hiperproduccion de IgE. Propuesta de nueva denominacion para una enfermedad alergica confundida con inmunodeficiencia. PL - Mexico TA - Rev Alerg Mex JT - Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) JID - 9438824 RN - 37341-29-0 (Immunoglobulin E) SB - IM EIN - Rev Alerg Mex. 2007 Sep-Oct;54(5):155 MH - Diagnosis, Differential MH - Humans MH - Hypersensitivity/*diagnosis/*immunology MH - Immunoglobulin E/*biosynthesis MH - Immunologic Deficiency Syndromes/*diagnosis RF - 25 EDAT- 2008/02/27 09:00 MHDA- 2008/07/17 09:00 CRDT- 2008/02/27 09:00 PHST- 2008/02/27 09:00 [pubmed] PHST- 2008/07/17 09:00 [medline] PHST- 2008/02/27 09:00 [entrez] PST - ppublish SO - Rev Alerg Mex. 2007 Jul-Aug;54(4):123-33.