PMID- 18310234 OWN - NLM STAT- MEDLINE DCOM- 20080624 LR - 20211020 IS - 1936-959X (Electronic) IS - 0195-6108 (Print) IS - 0195-6108 (Linking) VI - 29 IP - 4 DP - 2008 Apr TI - Intracranial stenting of severe symptomatic intracranial stenosis: results of 100 consecutive patients. PG - 781-5 LID - 10.3174/ajnr.A0922 [doi] AB - BACKGROUND AND PURPOSE: There are a few reports regarding the outcome evaluation of balloon-expandable intracranial stent placement (BEICS). The purpose of our study was to evaluate the outcome and factors related to the adverse events (AEs) of BEICS. MATERIALS AND METHODS: We evaluated 100 consecutive patients who underwent BEICS. We assessed the procedural success (residual stenosis < 50%), AEs (minor strokes, major strokes, and death), clinical outcome, and restenosis (> 50%) at 6 months. We also analyzed 18 factors including symptom patterns related to AE rate. Symptom patterns revealed 1) stable patients (n = 73) with improving, stationary, or resolved symptoms; and 2) unstable patients (n = 27) with gradual worsening or fluctuating symptoms (National Institutes of Health Stroke Scale [NIHSS] > or = 4) within 2 days before stent placement. RESULTS: The procedural success rate was 99%. Overall, there were 10 (10%) AEs within the 6 months: 4 (4%) minor strokes, 3 (3%) major strokes, and 3 (3%) deaths including a death from myocardial infarction. AE rate was 4.1% in stable and 25.9% in unstable patients. Restenosis at 6 months revealed 0% (0/59). Good outcome (modified Rankin Scale < or = 2) at 6 months was 97% (71/73) in stable and 67% (18/27) in unstable patients. Stepwise logistic regression model revealed that symptom pattern (unstable versus stable) was the only significant risk factor (OR, 8.167; 95% CI, 1.933-34.500; P = .004). CONCLUSION: BEICS revealed a low AE and good outcome rate at 6 months, especially in the stable patients. Midterm outcome was also favorable in the unstable patient group. FAU - Suh, D C AU - Suh DC AD - Department of Radiology, Asan Medical Center, University of Ulsan, College of Medicine, 388-One Pungnap-2 Dong, Songpa-Gu, Seoul 138-736, Korea. dcsuh@amc.seoul.kr FAU - Kim, J K AU - Kim JK FAU - Choi, J W AU - Choi JW FAU - Choi, B S AU - Choi BS FAU - Pyun, H W AU - Pyun HW FAU - Choi, Y J AU - Choi YJ FAU - Kim, M-H AU - Kim MH FAU - Yang, H R AU - Yang HR FAU - Ha, H I AU - Ha HI FAU - Kim, S J AU - Kim SJ FAU - Lee, D H AU - Lee DH FAU - Choi, C G AU - Choi CG FAU - Hahm, K D AU - Hahm KD FAU - Kim, J S AU - Kim JS LA - eng PT - Journal Article DEP - 20080229 PL - United States TA - AJNR Am J Neuroradiol JT - AJNR. American journal of neuroradiology JID - 8003708 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - *Angioplasty, Balloon MH - Basilar Artery/pathology MH - Carotid Artery, Internal/pathology MH - Constriction, Pathologic MH - Female MH - Humans MH - Intracranial Arteriosclerosis/complications/pathology/*therapy MH - Male MH - Middle Aged MH - Middle Cerebral Artery/pathology MH - *Stents MH - Stroke/etiology MH - Vertebral Artery/pathology PMC - PMC7978185 EDAT- 2008/03/04 09:00 MHDA- 2008/06/25 09:00 PMCR- 2009/04/01 CRDT- 2008/03/04 09:00 PHST- 2008/03/04 09:00 [pubmed] PHST- 2008/06/25 09:00 [medline] PHST- 2008/03/04 09:00 [entrez] PHST- 2009/04/01 00:00 [pmc-release] AID - ajnr.A0922 [pii] AID - 10.3174/ajnr.A0922 [doi] PST - ppublish SO - AJNR Am J Neuroradiol. 2008 Apr;29(4):781-5. doi: 10.3174/ajnr.A0922. Epub 2008 Feb 29.