PMID- 18319560 OWN - NLM STAT- MEDLINE DCOM- 20080523 LR - 20221207 IS - 1343-1420 (Print) IS - 1343-1420 (Linking) VI - 55 IP - 1-2 DP - 2008 Feb TI - Problems in three Japanese drug users with Human Immunodeficiency Virus infection. PG - 156-60 AB - Numbers of individuals infected with Human Immunodeficiency Virus (HIV) are increasing in Japan. The majority of them are Men who have sex with men and a part of them take drugs as 'Sex drug' at their sexual intercourse. Especially, Amyl nitrite, Methamphetamine, 5-methoxy-N, N-diisopropyltryptamine (5-MeO-DIPT; Foxy), and 3, 4-methylenedioxy- methamphetamine (MDMA; Ecstasy) are used, and they sometimes cause the physical and mental disorders. However, the actual drug inducing troubles among Japanese HIV-infected drug users had not yet been discussed enough. In this report, we describe three cases with HIV infection; a case developed severe neuroleptic malignant syndrome (NMS) after taking 5-MeO-DIPT, a case with persistent convulsion due to multiple drug intake and a case with rhabdomyolysis due to the non-subjective methamphetamine intake. Through these cases, we raise and discuss several underlying problems associated with drug use among HIV-infected individuals. FAU - Kuwahara, Takeshi AU - Kuwahara T AD - Department of Pharmacy, Osaka National Hospital, National Hospital Organization, Osaka, Japan. FAU - Nakakura, Takahiro AU - Nakakura T FAU - Oda, Sachiko AU - Oda S FAU - Mori, Masahiko AU - Mori M FAU - Uehira, Tomoko AU - Uehira T FAU - Okamoto, Gaku AU - Okamoto G FAU - Yoshino, Munehiro AU - Yoshino M FAU - Sasakawa, Atsushi AU - Sasakawa A FAU - Yajima, Keishiro AU - Yajima K FAU - Umemoto, Aiko AU - Umemoto A FAU - Takada, Kiyonori AU - Takada K FAU - Makie, Toshio AU - Makie T FAU - Yamamoto, Yoshihiko AU - Yamamoto Y LA - eng PT - Case Reports PT - Journal Article PL - Japan TA - J Med Invest JT - The journal of medical investigation : JMI JID - 9716841 RN - 12D06G8W8E (5-methoxy-N,N-diisopropyltryptamine) RN - 3VMW6141KC (5-Methoxytryptamine) RN - 44RAL3456C (Methamphetamine) RN - 8017-89-8 (Amyl Nitrite) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - 5-Methoxytryptamine/adverse effects/analogs & derivatives MH - Adult MH - Amyl Nitrite/adverse effects MH - Antiretroviral Therapy, Highly Active MH - Asian People MH - Drug Interactions MH - HIV Infections/*complications/drug therapy MH - Humans MH - Male MH - Methamphetamine/adverse effects MH - N-Methyl-3,4-methylenedioxyamphetamine/adverse effects MH - Neuroleptic Malignant Syndrome/*etiology MH - Rhabdomyolysis/*etiology MH - Seizures/*etiology MH - Substance-Related Disorders/*complications EDAT- 2008/03/06 09:00 MHDA- 2008/05/24 09:00 CRDT- 2008/03/06 09:00 PHST- 2008/03/06 09:00 [pubmed] PHST- 2008/05/24 09:00 [medline] PHST- 2008/03/06 09:00 [entrez] AID - JST.JSTAGE/jmi/55.156 [pii] AID - 10.2152/jmi.55.156 [doi] PST - ppublish SO - J Med Invest. 2008 Feb;55(1-2):156-60. doi: 10.2152/jmi.55.156.