PMID- 18327429
OWN - NLM
STAT- MEDLINE
DCOM- 20080821
LR  - 20080310
IS  - 1684-1182 (Print)
IS  - 1684-1182 (Linking)
VI  - 41
IP  - 1
DP  - 2008 Feb
TI  - Prevalence of Blomia tropicalis in wheezing children in central Taiwan.
PG  - 68-73
AB  - BACKGROUND AND PURPOSE: In a previous study, we found that wheezing children in 
      rural central Taiwan had a significantly lower average sensitization rate to 
      Dermatophagoides pteronyssinus (Der p) than those in Taipei city. We propose that 
      Blomia tropicalis (Blo t) might be the major mite allergen in rural central 
      Taiwan. METHODS: Using the preserved sera from our previous study, we 
      retrospectively measured specific immunoglobulin E (IgE) antibody to Blo t and 
      analyzed the correlation between Blo t and Der p in wheezing children in rural 
      central Taiwan. A total of 2206 children with physician-diagnosed asthma and 
      wheezing were enrolled and categorized among five age groups. The sensitization 
      rate and level of specific IgE antibody to Blo t were analyzed. RESULTS: The 
      age-specific sensitization rates and the level of specific IgE antibody to either 
      Blo t or Der p increased progressively with increasing age, being greatest in the 
      age group 8 to 12 years. A significant positive correlation existed between 
      sensitization rate and age for both Blo t and Der p (p=0.001). Specific IgE 
      antibody to Blo t was undetectable in patients younger than 1.5 years. A 
      significant positive correlation also existed between age and anti-Blo t IgE 
      antibody level (p<0.003). However, the allergen-specific IgE level was lower for 
      Blo t than Der p (p<0.005) in all age groups. CONCLUSIONS: Blo t might be the 
      major mite allergen to associated with early wheeze and atopic asthma in rural 
      central Taiwan.
FAU - Yu, Meng-Kung
AU  - Yu MK
AD  - Department of Pediatrics, Changhua Christian Hospital, Changhua, Taiwan.
FAU - Lin, Ching-Yuang
AU  - Lin CY
FAU - Chen, Woan-Ling
AU  - Chen WL
FAU - Chen, Ching-Tung
AU  - Chen CT
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - J Microbiol Immunol Infect
JT  - Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
JID - 100956211
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Age Factors
MH  - Allergens/immunology
MH  - Animals
MH  - Asthma/blood/*immunology
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood/immunology
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Mites/*immunology
MH  - Prevalence
MH  - Respiratory Sounds/*immunology
MH  - Retrospective Studies
MH  - Rural Population
MH  - Taiwan
EDAT- 2008/03/11 09:00
MHDA- 2008/08/22 09:00
CRDT- 2008/03/11 09:00
PHST- 2008/03/11 09:00 [pubmed]
PHST- 2008/08/22 09:00 [medline]
PHST- 2008/03/11 09:00 [entrez]
PST - ppublish
SO  - J Microbiol Immunol Infect. 2008 Feb;41(1):68-73.