PMID- 18328409
OWN - NLM
STAT- MEDLINE
DCOM- 20080630
LR  - 20211020
IS  - 0899-9007 (Print)
IS  - 0899-9007 (Linking)
VI  - 24
IP  - 4
DP  - 2008 Apr
TI  - Nutrient intake from habitual oral diet in patients with severe short bowel 
      syndrome living in the southeastern United States.
PG  - 330-9
LID - 10.1016/j.nut.2007.12.016 [doi]
AB  - OBJECTIVES: Little data are published on the habitual home oral diet of patients 
      with short bowel syndrome (SBS). METHODS: We assessed nutrient intake from oral 
      food and beverages in 19 stable patients with severe SBS who live in the 
      southeastern United States. Intestinal absorption of energy, fat, nitrogen (N), 
      and carbohydrate (CHO) was determined in a metabolic ward. RESULTS: We studied 12 
      women and 7 men, age 48 +/- 3 y of age (mean +/- SE) receiving parenteral 
      nutrition for 31 +/- 8 mo following massive small bowel resection (118 +/- 25 cm 
      residual small bowel). The patients demonstrated severe malabsorption of energy 
      (59 +/- 3% of oral intake), fat (41 +/- 5%), N (42 +/- 5%) and CHO (76 +/- 3%). 
      Oral energy intake was 2656 +/- 242 kcal/d (39 +/- 3 kcal/kg/d) and oral protein 
      intake was 1.4 +/- 0.1 g/kg/d. Food/beverage intake constituted 49 +/- 4% of 
      total (enteral plus parenteral) daily fluid intake, 66 +/- 4% of total daily kcal 
      and 58 +/- 5% of total daily N intake. Oral fat intake averaged 92 +/- 11 g/day ( 
      approximately 35% of total oral energy). Oral fluid intake averaged 2712 +/- 240 
      ml/d, primarily from water, soft drinks, sweet tea and coffee. Simple sugars 
      comprised 42 +/- 3% of oral CHO intake. Usual dietary intake of multiple 
      micronutrients were below the Recommended Dietary Allowances (RDA) in a large 
      percentage of patients: vitamin A (47%), vitamin D (79%), vitamin E (79%), 
      vitamin K (63%), thiamine (42%), vitamin B6 (68%), vitamin B12 (11%), vitamin C 
      (58%), folate (37%), iron (37%), calcium (63%), magnesium (79%) and zinc (68%). 
      Only seven patients (37%) were taking oral multivitamin-mineral supplements and 
      only six subjects (32%) were taking oral iron and calcium supplements, 
      respectively. CONCLUSION: In these SBS patients, an oral diet provided a 
      significant proportion of daily nutrient intake. The types of foods and fluids 
      consumed are likely to worsen malabsorption and thus increase PN requirements. 
      Oral intake of essential micronutrients was very low in a significant proportion 
      of these individuals.
FAU - Estivariz, Concepcion F
AU  - Estivariz CF
AD  - Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, 
      USA.
FAU - Luo, Menghua
AU  - Luo M
FAU - Umeakunne, Kayellen
AU  - Umeakunne K
FAU - Bazargan, Niloofar
AU  - Bazargan N
FAU - Galloway, John R
AU  - Galloway JR
FAU - Leader, Lorraine M
AU  - Leader LM
FAU - Ziegler, Thomas R
AU  - Ziegler TR
LA  - eng
GR  - R01 DK055850-02/DK/NIDDK NIH HHS/United States
GR  - M01 RR000039/RR/NCRR NIH HHS/United States
GR  - R01 DK055850-01A1/DK/NIDDK NIH HHS/United States
GR  - R01 DK055850/DK/NIDDK NIH HHS/United States
GR  - R01 DK055850-04/DK/NIDDK NIH HHS/United States
GR  - UL1 TR000454/TR/NCATS NIH HHS/United States
GR  - K24 RR023356/RR/NCRR NIH HHS/United States
GR  - R01 DK055850-03/DK/NIDDK NIH HHS/United States
GR  - RR00039/RR/NCRR NIH HHS/United States
GR  - R01 DK055850-03S1/DK/NIDDK NIH HHS/United States
GR  - R01 DK55850/DK/NIDDK NIH HHS/United States
GR  - R01 DK055850-05/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Nutrition
JT  - Nutrition (Burbank, Los Angeles County, Calif.)
JID - 8802712
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
RN  - 0 (Micronutrients)
RN  - 0 (Minerals)
RN  - 0 (Vitamins)
RN  - N762921K75 (Nitrogen)
SB  - IM
MH  - Adaptation, Physiological
MH  - Dietary Carbohydrates/administration & dosage/pharmacokinetics
MH  - Dietary Fats/administration & dosage/pharmacokinetics
MH  - Dietary Proteins/administration & dosage/pharmacokinetics
MH  - Dietary Supplements
MH  - Energy Intake
MH  - Energy Metabolism
MH  - *Feeding Behavior
MH  - Female
MH  - Humans
MH  - Intestinal Absorption/*physiology
MH  - Intestines/physiology
MH  - Male
MH  - Micronutrients/*administration & dosage/metabolism
MH  - Middle Aged
MH  - Minerals/administration & dosage/metabolism
MH  - Nitrogen/metabolism
MH  - Nutrition Assessment
MH  - Nutritional Physiological Phenomena/*physiology
MH  - *Nutritional Requirements
MH  - Severity of Illness Index
MH  - Short Bowel Syndrome/*metabolism/pathology
MH  - Southeastern United States
MH  - Vitamins/administration & dosage/metabolism
PMC - PMC2441845
MID - NIHMS42926
EDAT- 2008/03/11 09:00
MHDA- 2008/07/01 09:00
PMCR- 2009/04/01
CRDT- 2008/03/11 09:00
PHST- 2007/05/29 00:00 [received]
PHST- 2007/11/05 00:00 [revised]
PHST- 2007/12/20 00:00 [accepted]
PHST- 2008/03/11 09:00 [pubmed]
PHST- 2008/07/01 09:00 [medline]
PHST- 2008/03/11 09:00 [entrez]
PHST- 2009/04/01 00:00 [pmc-release]
AID - S0899-9007(08)00003-8 [pii]
AID - 10.1016/j.nut.2007.12.016 [doi]
PST - ppublish
SO  - Nutrition. 2008 Apr;24(4):330-9. doi: 10.1016/j.nut.2007.12.016.