PMID- 18335509 OWN - NLM STAT- MEDLINE DCOM- 20080805 LR - 20161124 IS - 0091-2751 (Print) IS - 0091-2751 (Linking) VI - 36 IP - 4 DP - 2008 May TI - Four-dimensional sonography with B-flow imaging and spatiotemporal image correlation for visualization of the fetal heart. PG - 204-7 LID - 10.1002/jcu.20478 [doi] AB - PURPOSE: To use B-flow imaging with 4-dimensional (4D) sonography and spatiotemporal image correlation (STIC) in the evaluation of normal fetal heart and congenital heart disease during pregnancy. METHOD: Volume data sets of the fetal heart were acquired with automated transverse and longitudinal sweeps of the anterior chest wall. We studied 13 normal fetuses and 2 fetuses with congenital heart disease (1 double-outlet right ventricle and 1 hypoplastic left heart syndrome) at gestation ages ranging from 13 to 39 weeks using transabdominal 4D B-flow sonography with STIC (4D BF-STIC). RESULTS: 4D BF-STIC demonstrated dynamic angiographic features in both normal and abnormal fetal hearts. 4D BF-STIC images could not be obtained in 2 normal fetuses at 18.1 and 33.1 weeks because of the high fetal heart rate and inappropriate fetal position. In normal fetal heart, characteristic hemodynamic changes in both atria and ventricles were clearly demonstrated in systole and diastole. 4D BF-STIC also allowed visualization of the relationship, size, and course of the outflow tracts, thus helping the examiner to better understand the relationships between the vessels. In a case of hypoplastic left heart syndrome, dramatic hemodynamic changes including the right atrium, right ventricle, and pulmonary artery were evident. In a case of double-outlet right ventricle with ventricular septal defect, left-to-right shunt flow through a ventricular septal defect was clearly shown, as were great arteries originating in parallel from the right ventricle. CONCLUSION: 4D BF-STIC provides a means of real-time 3-dimensional evaluation of fetal intracardiac and extracardiac hemodynamics in the second and third trimesters. This novel technique assists in the evaluation of fetal cardiac hemodynamics and may play an important role in future fetal cardiac research and in the evaluation of congenital heart disease in the fetus. CI - (c) 2008 Wiley Periodicals, Inc. J Clin Ultrasound, 2008. FAU - Hata, Toshiyuki AU - Hata T AD - Department of Perinatology and Gynecology, Kagawa University School of Medicine, 1750-1 Ikenobe, Miki, Kagawa 761-0793, Japan. FAU - Dai, Shu-Yan AU - Dai SY FAU - Inubashiri, Eisuke AU - Inubashiri E FAU - Kanenishi, Kenji AU - Kanenishi K FAU - Tanaka, Hirokazu AU - Tanaka H FAU - Yanagihara, Toshihiro AU - Yanagihara T FAU - Araki, Seiko AU - Araki S LA - eng PT - Journal Article PL - United States TA - J Clin Ultrasound JT - Journal of clinical ultrasound : JCU JID - 0401663 SB - IM MH - *Coronary Circulation MH - *Echocardiography, Four-Dimensional MH - Female MH - Fetal Heart/*diagnostic imaging/*embryology MH - Gestational Age MH - Heart Defects, Congenital/diagnostic imaging MH - Humans MH - Image Processing, Computer-Assisted MH - Pregnancy MH - Pregnancy Trimester, Second MH - Pregnancy Trimester, Third EDAT- 2008/03/13 09:00 MHDA- 2008/08/06 09:00 CRDT- 2008/03/13 09:00 PHST- 2008/03/13 09:00 [pubmed] PHST- 2008/08/06 09:00 [medline] PHST- 2008/03/13 09:00 [entrez] AID - 10.1002/jcu.20478 [doi] PST - ppublish SO - J Clin Ultrasound. 2008 May;36(4):204-7. doi: 10.1002/jcu.20478.