PMID- 18340540
OWN - NLM
STAT- MEDLINE
DCOM- 20080821
LR  - 20220408
IS  - 1387-1307 (Print)
IS  - 1387-1307 (Linking)
VI  - 22
IP  - 2
DP  - 2008 Apr
TI  - Multicenter evaluation of noninvasive cardiac output measurement by bioreactance 
      technique.
PG  - 113-9
LID - 10.1007/s10877-008-9112-5 [doi]
AB  - OBJECTIVES: Bioreactance, the analysis of intrabeat variations in phase of a 
      transthoracic voltage in response to an applied high frequency transthoracic 
      current, was recently introduced for noninvasive cardiac output measurement 
      (NICOM). We evaluated NICOM compared to thermo- dilution (TD) in several clinical 
      settings. METHODS: 111 patients with a clinical indication for TD cardiac output 
      (CO) measurement were recruited at five centers, including patients in cardiac 
      catheterization laboratories, cardiac care units and intensive care units. CO 
      measurements were made simulta- neously with TD and the bioreactance method and 
      compared by regression analysis. RESULTS: For studies in the intensive care 
      units, TD-based CO and NICOM were highly correlated (r = 0.78, P < 0.0001) and 
      did not differ significantly from each other (P = 0.55). Results in the cardiac 
      catheterization laboratory were similar (r = 0.71, P < 0.001; P = 0.28 NICOM 
      versus TD). In subsets of patients, NICOM was shown to be better corre- lated 
      with TD-CO than CO obtained with the Fick method or with standard 
      bioimpedance-based measurements of CO. CONCLUSIONS: On average, compared to TD, 
      bioreactance- based NICOM has acceptable accuracy in challenging clinical 
      environments. Availability of such a tool may allow clinicians to have 
      information about CO in patients where this information is not currently 
      available to help diagnosis and guide therapy.
FAU - Raval, Nirav Y
AU  - Raval NY
AD  - Atlanta Cardiology Group, 5665 Peachtree Dunwoody Road, Suite 172, Atlanta, GA 
      30342, USA. nraval@acgmd.com
FAU - Squara, Pierre
AU  - Squara P
FAU - Cleman, Michael
AU  - Cleman M
FAU - Yalamanchili, Kishore
AU  - Yalamanchili K
FAU - Winklmaier, Michael
AU  - Winklmaier M
FAU - Burkhoff, Daniel
AU  - Burkhoff D
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20080314
PL  - Netherlands
TA  - J Clin Monit Comput
JT  - Journal of clinical monitoring and computing
JID - 9806357
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Cardiac Output
MH  - *Cardiography, Impedance/statistics & numerical data
MH  - Electric Impedance
MH  - Electromagnetic Phenomena
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Physiologic/methods
MH  - Myocardial Contraction/physiology
MH  - Pulse
MH  - Regression Analysis
MH  - Reproducibility of Results
MH  - *Thermodilution/statistics & numerical data
EDAT- 2008/03/15 09:00
MHDA- 2008/08/22 09:00
CRDT- 2008/03/15 09:00
PHST- 2007/12/12 00:00 [received]
PHST- 2008/02/11 00:00 [accepted]
PHST- 2008/03/15 09:00 [pubmed]
PHST- 2008/08/22 09:00 [medline]
PHST- 2008/03/15 09:00 [entrez]
AID - 10.1007/s10877-008-9112-5 [doi]
PST - ppublish
SO  - J Clin Monit Comput. 2008 Apr;22(2):113-9. doi: 10.1007/s10877-008-9112-5. Epub 
      2008 Mar 14.