PMID- 18343349
OWN - NLM
STAT- MEDLINE
DCOM- 20080624
LR  - 20081023
IS  - 0002-9394 (Print)
IS  - 0002-9394 (Linking)
VI  - 145
IP  - 6
DP  - 2008 Jun
TI  - Spectral-domain Cirrus high-definition optical coherence tomography is better 
      than time-domain Stratus optical coherence tomography for evaluation of macular 
      pathologic features in uveitis.
PG  - 1018-1022
LID - 10.1016/j.ajo.2008.01.021 [doi]
AB  - PURPOSE: To compare high-definition (HD) spectral-domain optical coherence 
      tomography [SD-OCT] (Cirrus HD-OCT; Carl Zeiss, Dublin, California, USA) with 
      time-domain optical coherence tomography [TD-OCT] (Stratus version 4; Carl Zeiss) 
      for imaging macula in patients of uveitis. DESIGN: Interventional case series. 
      METHODS: Thirty consecutive patients (51 eyes) with uveitis of various causes 
      with vitreous haze of 1+ or worse were treated in an institutional setting. All 
      patients had their vitreous haze graded and OCT scans both on TD-OCT (Stratus) 
      and SD-OCT (Cirrus). Information obtained from Cirrus OCT scans was compared with 
      that obtained from Stratus OCT scans. RESULTS: Overall, for all grades of media 
      clarity, the macula was interpreted as normal in 30 eyes (58.8%) on Stratus OCT 
      and 26 eyes (50.9%) on Cirrus OCT and abnormal in 15 eyes (29.4%) on Stratus OCT 
      and 24 eyes (47.0%) on Cirrus OCT, whereas poor scan quality deterred any 
      interpretation in six eyes (10.0%) on Stratus OCT and only in one eye (1.8%) on 
      Cirrus OCT. Additional information on Cirrus OCT could be obtained in nine 
      (21.9%) of 41 eyes with grade 1+ vitreous haze, six (75%) of eight eyes with 
      grade 2+ vitreous haze, and one eye (50%) with vitreous haze of 3+. CONCLUSIONS: 
      Our preliminary results suggest that SD Cirrus HD-OCT has an advantage over TD 
      Stratus OCT in uveitic eyes by providing better identification of normal and 
      pathologic structure in patients with poor media clarity.
FAU - Gupta, Vishali
AU  - Gupta V
AD  - Department of Ophthalmology, Advanced Eye Centre, Post-Graduate Institute of 
      Medical Education and Research, Chandigarh, India.
FAU - Gupta, Pawan
AU  - Gupta P
FAU - Singh, Ramandeep
AU  - Singh R
FAU - Dogra, Mangat R
AU  - Dogra MR
FAU - Gupta, Amod
AU  - Gupta A
LA  - eng
PT  - Case Reports
PT  - Comparative Study
PT  - Journal Article
DEP - 20080317
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
CIN - Am J Ophthalmol. 2008 Oct;146(4):626-7; author reply 627-8. PMID: 18804564
MH  - Adolescent
MH  - Adult
MH  - *Diagnostic Techniques, Ophthalmological
MH  - Female
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Tomography, Optical Coherence/*methods
MH  - Uveitis/*diagnosis
EDAT- 2008/03/18 09:00
MHDA- 2008/06/25 09:00
CRDT- 2008/03/18 09:00
PHST- 2007/12/15 00:00 [received]
PHST- 2008/01/16 00:00 [revised]
PHST- 2008/01/21 00:00 [accepted]
PHST- 2008/03/18 09:00 [pubmed]
PHST- 2008/06/25 09:00 [medline]
PHST- 2008/03/18 09:00 [entrez]
AID - S0002-9394(08)00083-4 [pii]
AID - 10.1016/j.ajo.2008.01.021 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2008 Jun;145(6):1018-1022. doi: 10.1016/j.ajo.2008.01.021. Epub 
      2008 Mar 17.