PMID- 18344035
OWN - NLM
STAT- MEDLINE
DCOM- 20080715
LR  - 20191210
IS  - 0340-9937 (Print)
IS  - 0340-9937 (Linking)
VI  - 33
IP  - 2
DP  - 2008 Mar
TI  - [STEMI network Essen-in-hospital results].
PG  - 148-52
LID - 10.1007/s00059-008-3119-z [doi]
AB  - BACKGROUND AND PURPOSE: The myocardial infarction network "Herzinfarktverbund 
      Essen", existing since 2004, was designed to introduce guideline therapy of ST 
      elevation myocardial infarction (STEMI) into everyday clinical practice using 
      primary percutaneous coronary intervention (PCI) as the preferred reperfusion 
      strategy, early prescribing recommended medication and optimizing patient's 
      pathway from the first symptom to rehabilitation in a city of 580,000 
      inhabitants. PATIENTS AND METHODS: In the 1st year, 489 patients were treated in 
      five high-volume PCI centers. 444 primary PCIs were performed (90.8%). RESULTS: 
      In-hospital mortality was 7.6% and thus lower than in other, historical STEMI 
      registers with similar baseline characteristics but lower PCI rate. The best risk 
      predictor was left ventricular function. Patients with an ejection fraction (EF) 
      <or= 30% had a 27 times higher mortality risk than those with normal EF. 
      Guideline-recommended medication was prescribed in 75% of patients 
      (acetylsalicylic acid [ASS], clopidogrel, beta-blockers, and statins) and in 71%, 
      respectively, with additional ACE inhibitor (five drugs). 72% of these patients 
      were referred to rehabilitation therapy. CONCLUSION: The "Herzinfarktverbund 
      Essen" demonstrates, that implementing guideline-conformal therapy into an urban 
      area may result in a lower in-hospital mortality, a higher rate of patients 
      prescribed recommended medication and a stronger patient adherence to ambulant 
      therapy.
FAU - Buchholz, Jochen
AU  - Buchholz J
AD  - Klinik fur Innere Medizin I und Kardiologie, Alfried Krupp Krankenhaus, Essen. 
      jochen.buchholz@krupp-krankenhaus.de
FAU - Naber, Christoph K
AU  - Naber CK
FAU - Budde, Thomas
AU  - Budde T
FAU - Koslowski, Bernd
AU  - Koslowski B
FAU - Hailer, Birgit
AU  - Hailer B
FAU - Jacksch, Rainer
AU  - Jacksch R
FAU - Sabin, Georg
AU  - Sabin G
FAU - Haude, Michael
AU  - Haude M
FAU - Erbel, Raimund
AU  - Erbel R
CN  - fur den Herzinfarktverbund Essen
LA  - ger
PT  - Evaluation Study
PT  - Journal Article
TT  - Hospitalphase der Patienten mit STEMI im Essener Herzinfarktverbund.
PL  - Germany
TA  - Herz
JT  - Herz
JID - 7801231
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Ambulatory Care
MH  - *Angioplasty, Balloon, Coronary
MH  - Cardiac Output, Low/mortality
MH  - Combined Modality Therapy
MH  - Delivery of Health Care, Integrated/*organization & administration
MH  - *Electrocardiography
MH  - Emergency Medical Services/*organization & administration
MH  - Female
MH  - Germany
MH  - Hospital Mortality
MH  - *Hospitalization
MH  - Humans
MH  - Length of Stay
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/diagnosis/mortality/*therapy
MH  - Patient Compliance
MH  - Practice Guidelines as Topic
MH  - Registries
MH  - Survival Rate
EDAT- 2008/03/18 09:00
MHDA- 2008/07/17 09:00
CRDT- 2008/03/18 09:00
PHST- 2008/03/18 09:00 [pubmed]
PHST- 2008/07/17 09:00 [medline]
PHST- 2008/03/18 09:00 [entrez]
AID - 10.1007/s00059-008-3119-z [doi]
PST - ppublish
SO  - Herz. 2008 Mar;33(2):148-52. doi: 10.1007/s00059-008-3119-z.