PMID- 18344754
OWN - NLM
STAT- MEDLINE
DCOM- 20080520
LR  - 20161124
IS  - 1057-0829 (Print)
IS  - 1057-0829 (Linking)
VI  - 17
IP  - 2
DP  - 2008 Mar
TI  - Optic nerve head drusen and visual field loss in normotensive and hypertensive 
      eyes.
PG  - 100-4
LID - 10.1097/IJG.0b013e31814b995a [doi]
AB  - OBJECTIVE: To compare visual field loss (VFL) in eyes with optic nerve head 
      drusen (ONHD) with or without ocular hypertension (OHT). METHODS: The records of 
      all patients aged 45 years or older with a diagnosis of ONHD at 2 centers were 
      reviewed. OHT was defined as intraocular pressure >or=22 mm Hg. We categorized 
      ONHD into 3 grades based on visibility on disc photographs. RESULTS: We 
      identified 22 eyes (13 patients) with both ONHD and OHT and 81 normotensive eyes 
      (47 patients) with ONHD. VFL was present in 20/22 (90.9%) of hypertensive eyes 
      compared with 54/81 (66.7%) of normotensive eyes (P=0.03, Fisher exact test). 
      Drusen grade III and OHT were both independently and significantly associated 
      with greater incidence of VFL (logistic regression analysis). CONCLUSIONS: VFL 
      occurs more frequently in eyes with ONHD that also have OHT. Eyes with grade III 
      ONHD are at increased risk for VFL compared to eyes with grade I drusen with the 
      same intraocular pressure status. Patients with OHT and ONHD should undergo close 
      surveillance for disease progression and be treated appropriately to prevent 
      additional VFL.
FAU - Grippo, Tomas M
AU  - Grippo TM
AD  - Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, 
      USA.
FAU - Shihadeh, Wisam A
AU  - Shihadeh WA
FAU - Schargus, Marc
AU  - Schargus M
FAU - Gramer, Eugen
AU  - Gramer E
FAU - Tello, Celso
AU  - Tello C
FAU - Liebmann, Jeffrey M
AU  - Liebmann JM
FAU - Ritch, Robert
AU  - Ritch R
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Glaucoma
JT  - Journal of glaucoma
JID - 9300903
SB  - IM
EIN - J Glaucoma. 2010 Feb;19(2):150
MH  - Female
MH  - Humans
MH  - Intraocular Pressure
MH  - Male
MH  - Middle Aged
MH  - Ocular Hypertension/*complications/diagnosis/physiopathology
MH  - Optic Disk Drusen/*complications/diagnostic imaging/physiopathology
MH  - Ultrasonography
MH  - Vision Disorders/*complications/diagnosis/physiopathology
MH  - Visual Field Tests
MH  - *Visual Fields
EDAT- 2008/03/18 09:00
MHDA- 2008/05/21 09:00
CRDT- 2008/03/18 09:00
PHST- 2008/03/18 09:00 [pubmed]
PHST- 2008/05/21 09:00 [medline]
PHST- 2008/03/18 09:00 [entrez]
AID - 00061198-200803000-00003 [pii]
AID - 10.1097/IJG.0b013e31814b995a [doi]
PST - ppublish
SO  - J Glaucoma. 2008 Mar;17(2):100-4. doi: 10.1097/IJG.0b013e31814b995a.