PMID- 18346139
OWN - NLM
STAT- MEDLINE
DCOM- 20080922
LR  - 20161018
IS  - 0891-6640 (Print)
IS  - 0891-6640 (Linking)
VI  - 22
IP  - 2
DP  - 2008 Mar-Apr
TI  - Thromboelastographic tracings in retired racing greyhounds and in non-greyhound 
      dogs.
PG  - 374-9
LID - 10.1111/j.1939-1676.2008.0061.x [doi]
AB  - BACKGROUND: Bleeding disorders in patients with normal coagulation test results 
      are frequently reported in Greyhounds. The purpose of this study was to compare 
      Greyhounds to non-Greyhounds by thromboelastography (TEG). HYPOTHESIS: TEG 
      parameters in Greyhounds are different from those in non-Greyhounds. ANIMALS: 
      Forty-three healthy dogs (28 Greyhounds and 15 non-Greyhounds) based on the 
      results of physical examination, CBC, activated partial thromboplastin time, 
      prothrombin time, fibrinogen, and platelet count. MATERIALS AND METHODS: 
      Recalcified citrated native TEGs were performed in both groups; data were 
      compared using Student's, Mann-Whitney, and Pearson's statistical tests. RESULTS: 
      In Greyhounds, mean +/- SD were as follows: R-time 4.3 +/- 1.7 minutes, K-time 
      3.8 +/- 1.4 minutes, angle (alpha) 50.0 +/- 8.0 degrees , maximum amplitude (MA) 
      47.6 +/- 5.6 mm, clot strength (G) 4,647 +/- 1,097 dyn/cm2, and percent lysis at 
      60 minutes (LY60) 2.8 +/- 5.0%. In the non-Greyhounds they were R-time 3.7 +/- 
      1.6 minutes, K-time 2.5 +/- 0.9 minutes, angle 59.8 +/- 7.0 degrees , MA 53.1 +/- 
      5.6 mm, G 5,811 +/- 1,256 dyn/cm2, and LY60 3.1 +/- 2.5%. All parameters were 
      significantly different between the groups, except for R-time and LY60. 
      CONCLUSION: In Greyhounds, clotting kinetics are slower and clot strength are 
      weaker than in non-Greyhounds, supporting the increased tendency to bleed 
      observed after minor trauma or surgical procedures in the breed. The findings may 
      also be attributed to blood viscosity or to the concentration of citrate in the 
      sample (ie, Greyhounds have higher hematocrit and less plasma per unit volume).
FAU - Vilar, P
AU  - Vilar P
AD  - Department of Veterinary Clinical Sciences and Veterinary Teaching Hospital, The 
      Ohio State University, Columbus, OH 43210, USA. vilarsaavedra.1@osu.edu
FAU - Couto, C G
AU  - Couto CG
FAU - Westendorf, N
AU  - Westendorf N
FAU - Iazbik, C
AU  - Iazbik C
FAU - Charske, J
AU  - Charske J
FAU - Marin, L
AU  - Marin L
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080310
PL  - United States
TA  - J Vet Intern Med
JT  - Journal of veterinary internal medicine
JID - 8708660
SB  - IM
MH  - Animals
MH  - Blood Coagulation/*genetics
MH  - Blood Coagulation Tests/veterinary
MH  - Breeding
MH  - Dogs/*blood
MH  - Female
MH  - Hemostasis/genetics
MH  - Male
MH  - Reference Values
MH  - Thrombelastography/*veterinary
EDAT- 2008/03/19 09:00
MHDA- 2008/09/23 09:00
CRDT- 2008/03/19 09:00
PHST- 2008/03/19 09:00 [pubmed]
PHST- 2008/09/23 09:00 [medline]
PHST- 2008/03/19 09:00 [entrez]
AID - JVIM61 [pii]
AID - 10.1111/j.1939-1676.2008.0061.x [doi]
PST - ppublish
SO  - J Vet Intern Med. 2008 Mar-Apr;22(2):374-9. doi: 10.1111/j.1939-1676.2008.0061.x. 
      Epub 2008 Mar 10.