PMID- 18359130 OWN - NLM STAT- MEDLINE DCOM- 20100111 LR - 20091019 IS - 1558-1497 (Electronic) IS - 0197-4580 (Linking) VI - 30 IP - 12 DP - 2009 Dec TI - Association study of the HLA-A2 allele in Italian Alzheimer disease patients. PG - 2082-3 LID - 10.1016/j.neurobiolaging.2008.02.001 [doi] AB - Association of the A2 allele of the human leukocyte antigen (HLA) with Alzheimer disease (AD) is still controversial. The authors evaluated HLA-A2 association with AD in 173 Italian AD patients, considering also the possible interaction with APOE pattern, age of onset and gender. No evidence of any association was found. FAU - Guerini, Franca Rosa AU - Guerini FR AD - Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation IRCCS, Milan, Italy. fguerini@dongnocchi.it FAU - Calabrese, Elena AU - Calabrese E FAU - Agliardi, Cristina AU - Agliardi C FAU - Zanzottera, Milena AU - Zanzottera M FAU - Franceschi, Massimo AU - Franceschi M FAU - Grimaldi, Luigi Maria Edoardo AU - Grimaldi LM FAU - Nemni, Raffaello AU - Nemni R FAU - Ferrante, Pasquale AU - Ferrante P LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20080321 PL - United States TA - Neurobiol Aging JT - Neurobiology of aging JID - 8100437 RN - 0 (Apolipoprotein E4) RN - 0 (HLA-A2 Antigen) SB - IM MH - Age of Onset MH - Aged MH - Alleles MH - Alzheimer Disease/epidemiology/*genetics MH - Apolipoprotein E4/genetics MH - Female MH - Genetic Association Studies MH - Genotype MH - HLA-A2 Antigen/*genetics MH - Humans MH - Italy/epidemiology MH - Male MH - Middle Aged MH - Phenotype MH - Sequence Analysis, DNA MH - Sex Factors EDAT- 2008/03/25 09:00 MHDA- 2010/01/12 06:00 CRDT- 2008/03/25 09:00 PHST- 2007/08/06 00:00 [received] PHST- 2008/01/30 00:00 [revised] PHST- 2008/02/10 00:00 [accepted] PHST- 2008/03/25 09:00 [pubmed] PHST- 2010/01/12 06:00 [medline] PHST- 2008/03/25 09:00 [entrez] AID - S0197-4580(08)00043-2 [pii] AID - 10.1016/j.neurobiolaging.2008.02.001 [doi] PST - ppublish SO - Neurobiol Aging. 2009 Dec;30(12):2082-3. doi: 10.1016/j.neurobiolaging.2008.02.001. Epub 2008 Mar 21.