PMID- 18360851
OWN - NLM
STAT- MEDLINE
DCOM- 20080512
LR  - 20101118
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 71
IP  - 5
DP  - 2008 Apr 1
TI  - Prognostic value of ST-segment resolution after rescue percutaneous coronary 
      intervention. Data from the RICO survey.
PG  - 607-12
LID - 10.1002/ccd.21409 [doi]
AB  - OBJECTIVES: The goal of the present study was to test the impact of ST segment 
      resolution (STR) after rescue percutaneous coronary intervention (PCI) on the 
      short-term prognosis. BACKGROUND: The prognostic value of STR after rescue PCI 
      for acute ST elevation myocardial infarction (STEMI) remains undetermined. 
      METHODS: From the French regional database, we analyzed 168 consecutive patients 
      with STEMI and failed lysis, defined by <50 percent STR, who underwent rescue 
      PCI. Patients were classified into two groups according to the degree of STR from 
      the maximal ST-elevation measured on the single worst ECG lead before lysis and 
      after rescue PCI: the without STR group (<50% STR) vs. the with STR group (> or 
      =50%). RESULTS: After rescue PCI, 26 (15%) patients did not have STR and 142 
      (85%) patients did. No difference was observed between the two groups regarding 
      baseline characteristics, risk factors, and median time delay either from symptom 
      onset to thrombolysis or from failed lysis to rescue PCI. We observed a lower 
      proportion of patients with TIMI 2/3 flow post PCI in the without STR group 
      (respectively 61% vs. 97%, P < 0.001) but an increased use of intra-aortic 
      balloon counterpulsation (34% vs. 8%, P < 0.001) in this group. Thirty-day 
      mortality was markedly higher in the without STR group than in the with STR group 
      (27% vs. 9% respectively, P = 0.025). Moreover, multivariate analysis showed that 
      absence of STR (OR: 5.65; 95% CI: 1.24-25.67), was an independent prognostic 
      factor for mortality. CONCLUSIONS: We showed for the first time that analysis of 
      ST-segment resolution may be a simple reliable tool to identify patients at high 
      risk after rescue PCI, and may provide useful information for the elaboration of 
      therapeutic strategies.
CI  - Copyright 2008 Wiley-Liss, Inc.
FAU - Lorgis, Luc
AU  - Lorgis L
AD  - Service de Cardiologie, CHU Bocage, Bd Mal de Lattre de Tassigny, Dijon, France.
FAU - Zeller, Marianne
AU  - Zeller M
FAU - Dentan, Gilles
AU  - Dentan G
FAU - Laurent, Yves
AU  - Laurent Y
FAU - Taam, Jamal Abou
AU  - Taam JA
FAU - L'Huillier, Isabelle
AU  - L'Huillier I
FAU - Vincent-Martin, Michel
AU  - Vincent-Martin M
FAU - Makki, Hamid
AU  - Makki H
FAU - Cottin, Yves
AU  - Cottin Y
CN  - RICO Survey Working Group
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
CIN - Catheter Cardiovasc Interv. 2008 Apr 1;71(5):613. PMID: 18360852
MH  - Aged
MH  - Angioplasty, Balloon, Coronary/*adverse effects/instrumentation
MH  - Cardiovascular Diseases/*etiology/mortality
MH  - *Coronary Circulation
MH  - Electrocardiography
MH  - Female
MH  - France
MH  - Health Care Surveys
MH  - Humans
MH  - Intra-Aortic Balloon Pumping
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/drug therapy/mortality/physiopathology/*therapy
MH  - Odds Ratio
MH  - Prognosis
MH  - Prospective Studies
MH  - Registries
MH  - Risk Assessment
MH  - Stents
MH  - *Thrombolytic Therapy
MH  - Time Factors
MH  - Treatment Failure
MH  - Treatment Outcome
EDAT- 2008/03/25 09:00
MHDA- 2008/05/13 09:00
CRDT- 2008/03/25 09:00
PHST- 2008/03/25 09:00 [pubmed]
PHST- 2008/05/13 09:00 [medline]
PHST- 2008/03/25 09:00 [entrez]
AID - 10.1002/ccd.21409 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2008 Apr 1;71(5):607-12. doi: 10.1002/ccd.21409.