PMID- 18362558
OWN - NLM
STAT- MEDLINE
DCOM- 20080708
LR  - 20181201
IS  - 0148-7043 (Print)
IS  - 0148-7043 (Linking)
VI  - 60
IP  - 4
DP  - 2008 Apr
TI  - EMLA cream application without occlusive dressing before upper facial botulinum 
      toxin injection: a randomized, double-blind, placebo-controlled trial.
PG  - 353-6
LID - 10.1097/SAP.0b013e31812f6e0f [doi]
AB  - A randomized, double-blind, placebo-controlled clinical trial was conducted among 
      44 subjects to assess the efficacy of EMLA cream application without occlusive 
      dressing on pain on needling (PN) and pain on injection (PI) felt during multiple 
      botulinum toxin type A (BTA) injections for correction of hyperkinetic upper 
      facial lines. Mean PN score was less than PI score with high correlation and no 
      significant difference. Although both PN and PI scores (visual analog) were less 
      in the EMLA than placebo group, the difference was only statistically significant 
      for PN score. Time intervals between the cream application and BTA injections 
      beyond 60 minutes did not show lower pain score in either type of the pain.
FAU - Kashkouli, Mohsen Bahmani
AU  - Kashkouli MB
AD  - Rassoul Akram Hospital, Iran. bahmanik@yahoo.com
FAU - Salimi, Shabnam
AU  - Salimi S
FAU - Bakhtiari, Pejman
AU  - Bakhtiari P
FAU - Parvaresh, Mohammad Mehdi
AU  - Parvaresh MM
FAU - Sanjari, Mostafa Soltan
AU  - Sanjari MS
FAU - Naseripour, Masood
AU  - Naseripour M
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Ann Plast Surg
JT  - Annals of plastic surgery
JID - 7805336
RN  - 0 (Anesthetics, Local)
RN  - 0 (Lidocaine, Prilocaine Drug Combination)
RN  - 0 (Neuromuscular Agents)
RN  - 0 (Ointments)
RN  - 046O35D44R (Prilocaine)
RN  - 98PI200987 (Lidocaine)
RN  - EC 3.4.24.69 (Botulinum Toxins, Type A)
SB  - IM
MH  - Adult
MH  - Anesthetics, Local/*administration & dosage
MH  - Botulinum Toxins, Type A/*administration & dosage
MH  - Double-Blind Method
MH  - Face
MH  - Female
MH  - Humans
MH  - Lidocaine/*administration & dosage
MH  - Lidocaine, Prilocaine Drug Combination
MH  - Male
MH  - Middle Aged
MH  - Neuromuscular Agents/*administration & dosage
MH  - Ointments
MH  - Pain Measurement
MH  - Prilocaine/*administration & dosage
MH  - Prospective Studies
MH  - Skin Aging/*drug effects
EDAT- 2008/03/26 09:00
MHDA- 2008/07/09 09:00
CRDT- 2008/03/26 09:00
PHST- 2008/03/26 09:00 [pubmed]
PHST- 2008/07/09 09:00 [medline]
PHST- 2008/03/26 09:00 [entrez]
AID - 00000637-200804000-00004 [pii]
AID - 10.1097/SAP.0b013e31812f6e0f [doi]
PST - ppublish
SO  - Ann Plast Surg. 2008 Apr;60(4):353-6. doi: 10.1097/SAP.0b013e31812f6e0f.