PMID- 18364191 OWN - NLM STAT- MEDLINE DCOM- 20080721 LR - 20151119 IS - 1579-2242 (Electronic) IS - 0300-8932 (Linking) VI - 61 IP - 2 DP - 2008 Feb TI - [Usefulness of NT-ProBNP as a biomarker of clinical status in outpatients with chronic heart failure]. PG - 206-10 AB - The role of the amino-terminal fragment of probrain natriuretic peptide (NT-proBNP) in monitoring the clinical status of outpatients with chronic heart failure has not yet been fully established. Fifty-nine patients with chronic heart failure were followed up at an outpatient clinic. The serum NT-proBNP level was measured and clinical status was assessed according to New York Heart Association (NYHA) functional class and Framingham clinical criteria. A positive correlation was found between the NT-proBNP level, NYHA functional class and Framingham score (P< .001). Patients who presented with a Framingham score > 2 were more likely to be readmitted to hospital (31.8% vs. 0%; P< .001), to visit an emergency department (36.4% vs. 5.4%; P=.002), or to die (13.6% vs. 0%; P=.021). The NT-proBNP level was higher in patients who needed to be readmitted to hospital (P=.004) and in those who attended an emergency department for decompensation (P=.002). FAU - Casado, Jesus M AU - Casado JM AD - Servicio de Medicina Interna, Hospital Universitario de La Princesa, Madrid, Espana. casadocerrada@hotmail.com FAU - Diaz, Ana AU - Diaz A FAU - Suarez, Carmen AU - Suarez C LA - spa PT - English Abstract PT - Journal Article TT - Utilidad del NT-proBNP como marcador biologico de la situacion clinica en pacientes con insuficiencia cardiaca cronica seguidos de forma ambulatoria. PL - Spain TA - Rev Esp Cardiol JT - Revista espanola de cardiologia JID - 0404277 RN - 0 (Biomarkers) RN - 0 (Peptide Fragments) RN - 0 (pro-brain natriuretic peptide (1-76)) RN - 114471-18-0 (Natriuretic Peptide, Brain) SB - IM MH - Aged MH - Biomarkers/blood MH - Chronic Disease MH - Female MH - Follow-Up Studies MH - Heart Failure/*blood/*diagnosis MH - Humans MH - Male MH - Natriuretic Peptide, Brain/*blood MH - Peptide Fragments/*blood MH - Prospective Studies MH - Severity of Illness Index EDAT- 2008/03/28 09:00 MHDA- 2008/07/22 09:00 CRDT- 2008/03/28 09:00 PHST- 2008/03/28 09:00 [pubmed] PHST- 2008/07/22 09:00 [medline] PHST- 2008/03/28 09:00 [entrez] AID - 13116209 [pii] PST - ppublish SO - Rev Esp Cardiol. 2008 Feb;61(2):206-10.