PMID- 18370735
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20080328
IS  - 1557-8518 (Electronic)
IS  - 1540-4196 (Linking)
VI  - 4
IP  - 3
DP  - 2006 Fall
TI  - Metabolic syndrome and related insulin levels in obese children.
PG  - 172-8
LID - 10.1089/met.2006.4.172 [doi]
AB  - Insulin resistance syndrome is a cluster of metabolic abnormalities that is 
      accompanied with an increased risk of diabetes and cardiovascular diseases. This 
      has become an important problem in urban children due to their increasing levels 
      of obesity. A total of 535 obese 7-11- year-old students of all the primary 
      schools of the 6th district of Tehran were screened according to their waist 
      circumference and then confirmed according to the International Obesity Task 
      Force (IOTF) criteria. Waist circumference, fasting serum triglycerides, 
      high-density lipoprotein (HDL) cholesterol, blood pressure, fasting plasma 
      glucose, and insulin levels were measured. Response rate of the study was 96.3%. 
      The crude prevalence rate of metabolic syndrome in these children was 20.6%. 
      There was no significant difference between genders. Only 8.2% of the studied 
      children were without any of the criteria of the metabolic syndrome. The most 
      common metabolic abnormality was hypertriglyceridemia, and the less common one 
      was low HDL levels. Fasting blood sugar, triglyceride, HDL, blood pressure, and 
      waist circumference were all related to the metabolic syndrome with odds ratio of 
      9.6, 18.71, 6.12, 17.64, and 13.68, respectively. Moreover, insulin levels were 
      significantly higher in these children (12.25 +/- 5.25 vs. 10.75 +/- 4.25 
      AmicroIU/mL, p = 0.019). This difference was significant in girls with and 
      without metabolic syndrome, but such a difference was not detected in boys. The 
      prevalence of metabolic syndrome is high in Iranian obese children. Early 
      intervention in this population who will become our future obese adults is 
      needed, not only to increase their life quality, but also to decrease the future 
      burden of diabetes and cardiovascular diseases on the society.
FAU - Ebrahimpour, Pantea
AU  - Ebrahimpour P
AD  - Endocrinology and Metabolism Research Center, Doctor Shariati Hospital, Tehran 
      University of Medical Sciences, Tehran, Iran.
FAU - Fakhrzadeh, Hossein
AU  - Fakhrzadeh H
FAU - Pourebrahim, Rasoul
AU  - Pourebrahim R
FAU - Hamidi, Anahita
AU  - Hamidi A
FAU - Larijani, Bagher
AU  - Larijani B
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Metab Syndr Relat Disord
JT  - Metabolic syndrome and related disorders
JID - 101150318
EDAT- 2008/03/29 09:00
MHDA- 2008/03/29 09:01
CRDT- 2008/03/29 09:00
PHST- 2008/03/29 09:00 [pubmed]
PHST- 2008/03/29 09:01 [medline]
PHST- 2008/03/29 09:00 [entrez]
AID - 10.1089/met.2006.4.172 [doi]
PST - ppublish
SO  - Metab Syndr Relat Disord. 2006 Fall;4(3):172-8. doi: 10.1089/met.2006.4.172.