PMID- 18379300
OWN - NLM
STAT- MEDLINE
DCOM- 20080513
LR  - 20220318
IS  - 0363-8715 (Print)
IS  - 0363-8715 (Linking)
VI  - 32
IP  - 2
DP  - 2008 Mar-Apr
TI  - Differential diagnosis of benign or malignant intraductal papillary mucinous 
      neoplasm of the pancreas by multidetector row helical computed tomography: 
      evaluation of predictive factors by logistic regression analysis.
PG  - 191-7
LID - 10.1097/RCT.0b013e3180676d97 [doi]
AB  - OBJECTIVE: The purpose of this study is to evaluate predictive factors for 
      discriminating benign from malignant intraductal mucin-producing neoplasm (IPMN) 
      of the pancreas on multidetector row computed tomography (MDCT). MATERIALS AND 
      METHODS: Fifty-three patients with IPMN underwent MDCT, and the imaging and 
      pathological findings were evaluated. In patients with branch duct-type tumors, 
      sex and age of the patient, location, shape, size and multiplicity of the cystic 
      lesion, presence of mural nodule, and maximum diameter of main pancreatic duct 
      (MPD) dilatation were evaluated by logistic regression analysis. RESULTS: Tumors 
      were classified as main duct-type (n = 7) and branch duct-type (n = 46). Among 
      main duct-type tumors, all 7 lesions were diagnosed as malignant. Among 46 
      lesions of branch-type IPMN, 8 lesions were malignant, and 38 lesions were 
      benign. On adjusted logistic regression analysis, combination factor of main duct 
      dilatation and mural nodule or large cystic size had statistical significance for 
      the risk of malignancy in branch duct-type IPMN. CONCLUSIONS: Main duct-type IPMN 
      is highly suggestive for malignancy. Combination factors of main ductal dilation 
      and mural nodule, and main ductal dilation, and large cystic tumor size are 
      thought to be predictive factors for malignant branch-type IPMN.
FAU - Takeshita, Koji
AU  - Takeshita K
AD  - Department of Radiology, Teikyo University School of Medicine, Tokyo, Japan. 
      takesita@med.teikyo-u.ac.jp
FAU - Kutomi, Kimiko
AU  - Kutomi K
FAU - Takada, Koichi
AU  - Takada K
FAU - Haruyama, Takahiro
AU  - Haruyama T
FAU - Fukushima, Junichi
AU  - Fukushima J
FAU - Aida, Rei
AU  - Aida R
FAU - Takada, Tadahiro
AU  - Takada T
FAU - Furui, Shigeru
AU  - Furui S
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - J Comput Assist Tomogr
JT  - Journal of computer assisted tomography
JID - 7703942
RN  - 0 (Contrast Media)
RN  - 4419T9MX03 (Iohexol)
SB  - IM
MH  - Adenocarcinoma, Mucinous/*diagnosis/surgery
MH  - Adult
MH  - Aged
MH  - Carcinoma, Pancreatic Ductal/*diagnosis/surgery
MH  - Carcinoma, Papillary/*diagnosis/surgery
MH  - Contrast Media/administration & dosage
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Iohexol
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Pancreatic Neoplasms/*diagnosis/surgery
MH  - Predictive Value of Tests
MH  - Radiographic Image Enhancement/methods
MH  - Tomography, Spiral Computed/*methods/*statistics & numerical data
EDAT- 2008/04/02 09:00
MHDA- 2008/05/14 09:00
CRDT- 2008/04/02 09:00
PHST- 2008/04/02 09:00 [pubmed]
PHST- 2008/05/14 09:00 [medline]
PHST- 2008/04/02 09:00 [entrez]
AID - 00004728-200803000-00005 [pii]
AID - 10.1097/RCT.0b013e3180676d97 [doi]
PST - ppublish
SO  - J Comput Assist Tomogr. 2008 Mar-Apr;32(2):191-7. doi: 
      10.1097/RCT.0b013e3180676d97.