PMID- 18380216
OWN - NLM
STAT- MEDLINE
DCOM- 20080619
LR  - 20080402
IS  - 0177-5103 (Print)
IS  - 0177-5103 (Linking)
VI  - 78
IP  - 3
DP  - 2008 Jan 24
TI  - Herpesvirus infection in European flat oysters Ostrea edulis obtained from brood 
      stocks of various geographic origins and grown in Galicia (NW Spain).
PG  - 181-8
LID - 10.3354/dao01874 [doi]
AB  - We evaluated differences in productive traits and disease susceptibility among 
      Ostrea edulis stocks. We produced 4 to 5 families from each of 4 oyster 
      populations (Irish, Greek and 2 Galician) in a hatchery. Spat corresponding to 19 
      different families were transferred to a raft in the Ria de Arousa (Galicia, 
      Spain) for grow-out. Samples of each family were histologically processed every 
      month for 2 yr. One of the pathological conditions disclosed by histological 
      examination was characterised by the occurrence of numerous abnormal cells 
      throughout the connective tissue of various organs, showing hypertrophied nuclei 
      with marginated chromatin and a characteristic large intranuclear acidophilic 
      inclusion. Ultrastructural examination showed that the abnormal cells contained 
      herpesvirus-like particles. In situ hybridisation assay using a DNA probe 
      specific for Ostreid herpesvirus 1 (OsHV-1) confirmed that the abnormal cells 
      were infected by OsHV-1 or a closely related herpesvirus. All cases of this 
      pathological condition, except one, were detected during the first year of 
      grow-out; thus it was mostly restricted to juvenile stages. The disease was 
      detected in oysters of each origin but it was not found in all families of each 
      origin, thus suggesting significant parental influence in the susceptibility to 
      this disease or significant influence of the infective status of the parents on 
      the infection of the progeny (vertical transmission). This pathological condition 
      was likely responsible for oyster mortality to some extent during the first year 
      of grow-out.
FAU - da Silva, P Mirella
AU  - da Silva PM
AD  - Centro de Investigacions Marinas, Conselleria de Pesca e Asuntos Maritimos, Xunta 
      de Galicia, Aptdo. 13, 36620 Vilanova de Arousa, Spain.
FAU - Renault, Tristan
AU  - Renault T
FAU - Fuentes, Jose
AU  - Fuentes J
FAU - Villalba, Antonio
AU  - Villalba A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Dis Aquat Organ
JT  - Diseases of aquatic organisms
JID - 8807037
SB  - IM
MH  - Animals
MH  - Aquaculture
MH  - Connective Tissue/ultrastructure/virology
MH  - Disease Susceptibility
MH  - Geography
MH  - Herpesviridae/*physiology
MH  - In Situ Hybridization, Fluorescence
MH  - Ostrea/*virology
MH  - Spain
MH  - Time Factors
EDAT- 2008/04/03 09:00
MHDA- 2008/06/20 09:00
CRDT- 2008/04/03 09:00
PHST- 2008/04/03 09:00 [pubmed]
PHST- 2008/06/20 09:00 [medline]
PHST- 2008/04/03 09:00 [entrez]
AID - 10.3354/dao01874 [doi]
PST - ppublish
SO  - Dis Aquat Organ. 2008 Jan 24;78(3):181-8. doi: 10.3354/dao01874.