PMID- 1838279 OWN - NLM STAT- MEDLINE DCOM- 19920318 LR - 20120531 IS - 0914-7470 (Print) IS - 0914-7470 (Linking) VI - 4 IP - 3 DP - 1991 Sep TI - [Consideration on the mechanism of liver regeneration on experimental results]. PG - 222-9 AB - Liver has enough functional capacity and regeneration ability. Liver parenchymal cells are usually stable, and it is thought being at stage of Go in cell cycle. But liver cells are easily into progressive stage and the liver recovers its functions and volume after partial hepatectomy or liver injury. Usually the studies of liver regeneration are done by studying control of growth of isolated hepatocytes in primary culture in vitro, and by pathological considerations of experimental injured models of liver in vivo. In this paper, we considered known several hepatotrophic factors including our experimental results, and regeneration mechanisms by noticing appearance of albumin positive hepatocytes in injured Nagase analbuminemic rat (NAR). FAU - Niiya, M AU - Niiya M AD - Department of Internal Medicine I, Jikei University School of Medicine, Tokyo, Japan. FAU - Hasumura, S AU - Hasumura S FAU - Nagamori, S AU - Nagamori S LA - jpn PT - English Abstract PT - Journal Article PL - Japan TA - Hum Cell JT - Human cell JID - 8912329 RN - 0 (Albumins) RN - 0 (Growth Substances) RN - 0 (Interleukin-6) RN - 67256-21-7 (Hepatocyte Growth Factor) RN - 9007-49-2 (DNA) SB - IM MH - Aging/pathology MH - Albumins/metabolism MH - Animals MH - Cell Division MH - Cells, Cultured MH - DNA/biosynthesis MH - Extracellular Matrix MH - Growth Substances/physiology MH - Hepatectomy MH - Hepatocyte Growth Factor MH - Humans MH - Interleukin-6/physiology MH - Liver/*cytology/metabolism/physiology MH - Liver Cirrhosis, Experimental/pathology/physiopathology MH - *Liver Regeneration EDAT- 1991/09/01 00:00 MHDA- 1991/09/01 00:01 CRDT- 1991/09/01 00:00 PHST- 1991/09/01 00:00 [pubmed] PHST- 1991/09/01 00:01 [medline] PHST- 1991/09/01 00:00 [entrez] PST - ppublish SO - Hum Cell. 1991 Sep;4(3):222-9.