PMID- 18382985
OWN - NLM
STAT- MEDLINE
DCOM- 20080715
LR  - 20091119
IS  - 1019-5149 (Print)
IS  - 1019-5149 (Linking)
VI  - 18
IP  - 1
DP  - 2008 Jan
TI  - Hereditary neuropathy with liability to pressure palsies in a Turkish patient 
      (HNPP): a rare cause of entrapment neuropathies in young adults.
PG  - 82-4
AB  - Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal 
      dominant nerve disease usually caused by 1,5 Mb deletion on chromosome 
      17p11.2.2-p12, the region where the PMP-22 gene is located. The patients with 
      HNPP usually have relapsing and remitting entrapment neuropathies due to 
      compression. We present a 14-year-old male who had acute onset, right-sided ulnar 
      nerve entrapment at the elbow. He had electrophysiological findings of bilateral 
      ulnar nerve entrapments (more severe at the right side) at the elbow and 
      bilateral median nerve entrapment at the wrist. Genetic tests of the patient 
      demonstrated deletions in the 17p11.2 region. The patient underwent decompressive 
      surgery for ulnar nerve entrapment at the elbow and completely recovered two 
      months after the event. Although HNPP is extremely rare, it should be taken into 
      consideration in young adults with entrapment neuropathies.
FAU - Celik, Yahya
AU  - Celik Y
AD  - Trakya University School of Medicine Neurology, Edirne, Turkey. 
      celikyahyatr@yahoo.com
FAU - Kilincer, Cumhur
AU  - Kilincer C
FAU - Hamamcioglu, M Kemal
AU  - Hamamcioglu MK
FAU - Balci, Kemal
AU  - Balci K
FAU - Birgili, Baris
AU  - Birgili B
FAU - Cobanoglu, Sebahattin
AU  - Cobanoglu S
FAU - Utku, Ufuk
AU  - Utku U
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Turkey
TA  - Turk Neurosurg
JT  - Turkish neurosurgery
JID - 9423821
RN  - 0 (Myelin Proteins)
RN  - 0 (PMP22 protein, human)
SB  - IM
MH  - Adolescent
MH  - Chromosomes, Human, Pair 17
MH  - Elbow Joint/innervation
MH  - Gene Deletion
MH  - Hereditary Sensory and Motor Neuropathy/*genetics/*pathology
MH  - Humans
MH  - Male
MH  - Median Neuropathy/genetics/pathology
MH  - Myelin Proteins/*genetics
MH  - Turkey
MH  - Ulnar Nerve Compression Syndromes/*genetics/*pathology
EDAT- 2008/04/03 09:00
MHDA- 2008/07/17 09:00
CRDT- 2008/04/03 09:00
PHST- 2008/04/03 09:00 [pubmed]
PHST- 2008/07/17 09:00 [medline]
PHST- 2008/04/03 09:00 [entrez]
PST - ppublish
SO  - Turk Neurosurg. 2008 Jan;18(1):82-4.