PMID- 18395166
OWN - NLM
STAT- MEDLINE
DCOM- 20080604
LR  - 20171116
IS  - 1879-0828 (Electronic)
IS  - 0953-6205 (Linking)
VI  - 19
IP  - 3
DP  - 2008 May
TI  - Classical cardiovascular risk factors according to fasting plasma glucose levels.
PG  - 209-13
LID - 10.1016/j.ejim.2007.09.005 [doi]
AB  - BACKGROUND: To compare the prevalence of classical cardiovascular risk factors 
      (CVRF) and metabolic syndrome (MetS) in our population according to fasting 
      plasma glucose levels (FPG). METHODS: We have studied 344 subjects between 20-70 
      years of age, recruited in a Primary Care Clinic. Subjects were divided into four 
      groups according to their fasting plasma glucose (FPG) values: normal plasma 
      glucose (NG) when FPG < 5.6 mmol/L; FPG between 5.6 and 6.0 mmol/L (FPG1); FPG 
      between 6.1-6.9 mmol/L (FPG2); and diabetes (DM) FPG > or = 7 mmol/L or previous 
      diagnosis of diabetes. Cardiovascular risk factors (hypertension, TC/HDL-C index 
      and Apo B values), presence of the MetS and indirect measure of insulin 
      resistance (HOMA) were analyzed. RESULTS: Subjects with FPG2 have a prevalence of 
      classic CVRF and MetS similar to that observed in subjects with type 2 diabetes 
      mellitus (T2DM). The TC:HDL-C index > or = 5 in 56% and 57%, Apo B > or = 1.2 g/L 
      in 59% and 57%, hypertension in 60% and 54% of FPG2 and T2DM subjects, 
      respectively. MetS was diagnosed in 79% of FPG2 and 80% of T2DM. We found 
      significant differences with FPG1 group who presented low CVRF and MetS 
      proportion. CONCLUSION: In our population FPG2 and T2DM subjects show a similar 
      cardiovascular risk profile. On the other hand, such risk is significantly lower 
      in subjects with FPG between 5.6-6.0 mmol/L. These results might have practical 
      implications.
FAU - Martinez-Hervas, Sergio
AU  - Martinez-Hervas S
AD  - Endocrinology Service, University Clinical Hospital, Department of 
      Medicine-University of Valencia, Spain. smartinezhervas@hotmail.com
FAU - Romero, Pedro
AU  - Romero P
FAU - Hevilla, Enrique B
AU  - Hevilla EB
FAU - Real, Jose T
AU  - Real JT
FAU - Priego, Antonia
AU  - Priego A
FAU - Martin-Moreno, Jose M
AU  - Martin-Moreno JM
FAU - Carmena, Rafael
AU  - Carmena R
FAU - Ascaso, Juan F
AU  - Ascaso JF
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20071108
PL  - Netherlands
TA  - Eur J Intern Med
JT  - European journal of internal medicine
JID - 9003220
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Blood Glucose
MH  - Cardiovascular Diseases/*blood/*epidemiology
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/blood/epidemiology
MH  - Fasting/*blood
MH  - Female
MH  - Humans
MH  - Male
MH  - Metabolic Syndrome/*blood/*epidemiology
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Spain/epidemiology
EDAT- 2008/04/09 09:00
MHDA- 2008/06/05 09:00
CRDT- 2008/04/09 09:00
PHST- 2007/04/24 00:00 [received]
PHST- 2007/06/29 00:00 [revised]
PHST- 2007/09/27 00:00 [accepted]
PHST- 2008/04/09 09:00 [pubmed]
PHST- 2008/06/05 09:00 [medline]
PHST- 2008/04/09 09:00 [entrez]
AID - S0953-6205(07)00264-6 [pii]
AID - 10.1016/j.ejim.2007.09.005 [doi]
PST - ppublish
SO  - Eur J Intern Med. 2008 May;19(3):209-13. doi: 10.1016/j.ejim.2007.09.005. Epub 
      2007 Nov 8.