PMID- 18408607
OWN - NLM
STAT- MEDLINE
DCOM- 20080923
LR  - 20080417
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 40
IP  - 5
DP  - 2008 May
TI  - Increased carbohydrate oxidation after ingesting carbohydrate with added protein.
PG  - 903-12
LID - 10.1249/MSS.0b013e318164cb52 [doi]
AB  - PURPOSE: To examine the metabolic impact of including protein in a postexercise 
      carbohydrate supplement when ingested between two bouts of prolonged running 
      performed within the same day. METHODS: Six healthy men participated in two 
      trials separated by 14 d, each involving a 90-min treadmill run at 70% VO2max 
      followed by 4 h of recovery and a subsequent 60-min run at the same intensity. At 
      30-min intervals during recovery, participants ingested either a solution 
      containing 0.8 g.kg(-1)h(-1) of carbohydrate (CHO) or the same solution plus an 
      additional 0.3 g.kg(-1)h(-1) of whey protein isolate (CHO-PRO). Muscle biopsies 
      were obtained from the vastus lateralis at the beginning and end of the recovery 
      period, with a third muscle biopsy taken following the second treadmill run. 
      RESULTS: Despite higher insulinemic responses to the CHO-PRO solution than to the 
      CHO solution (P < 0.05), rates of muscle glycogen resynthesis during recovery 
      were not different between treatments (CHO = 12.3 +/- 2.2 and CHO-PRO = 12.1 +/- 
      2.7 mmol glucosyl units per kilogram of dry mass per hour). Furthermore, there 
      were no differences between treatments in muscle glycogen degradation during 
      subsequent exercise (CHO = 2.2 +/- 0.3 and CHO-PRO = 2.0 +/- 0.1 mmol glucosyl 
      units per kilogram of dry mass per minute). In contrast, whole-body carbohydrate 
      oxidation during the second run was significantly greater with the CHO-PRO 
      treatment than with the CHO treatment (48.4 +/- 2.2 and 41.7 +/- 2.6 
      mg.kg(-1)min(-1), respectively; P < 0.01). CONCLUSION: These data show that the 
      inclusion of protein in a carbohydrate-recovery supplement can increase the 
      oxidation of extramuscular carbohydrate sources during subsequent exercise 
      without altering the rate of muscle glycogen degradation.
FAU - Betts, James A
AU  - Betts JA
AD  - Sport and Exercise Science, University of Bath, Bath, United Kingdom. 
      J.Betts@bath.ac.uk
FAU - Williams, Clyde
AU  - Williams C
FAU - Boobis, Les
AU  - Boobis L
FAU - Tsintzas, Kostas
AU  - Tsintzas K
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Carbohydrates)
RN  - 0 (Proteins)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Adult
MH  - Blood Gas Analysis
MH  - *Carbohydrate Metabolism
MH  - Carbohydrates/administration & dosage
MH  - Double-Blind Method
MH  - Exercise Test
MH  - Glycogen/metabolism
MH  - Humans
MH  - Male
MH  - Muscle, Skeletal/*metabolism
MH  - Oxygen Consumption/physiology
MH  - Physical Endurance/*physiology
MH  - Proteins/administration & dosage/*metabolism
MH  - Running/*physiology
MH  - Statistics, Nonparametric
MH  - Time Factors
MH  - Urinalysis
EDAT- 2008/04/15 09:00
MHDA- 2008/09/24 09:00
CRDT- 2008/04/15 09:00
PHST- 2008/04/15 09:00 [pubmed]
PHST- 2008/09/24 09:00 [medline]
PHST- 2008/04/15 09:00 [entrez]
AID - 10.1249/MSS.0b013e318164cb52 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2008 May;40(5):903-12. doi: 10.1249/MSS.0b013e318164cb52.