PMID- 18412619
OWN - NLM
STAT- MEDLINE
DCOM- 20080701
LR  - 20080416
IS  - 1460-9568 (Electronic)
IS  - 0953-816X (Linking)
VI  - 27
IP  - 8
DP  - 2008 Apr
TI  - Changes in Fos expression in the accessory olfactory bulb of sexually experienced 
      male rats after exposure to female urinary pheromones.
PG  - 1980-8
LID - 10.1111/j.1460-9568.2008.06169.x [doi]
AB  - We studied Fos-immunoreactive (Fos-ir) structures in the accessory olfactory bulb 
      (AOB) of rats after the vomeronasal organ was exposed to urine. Exposure of the 
      vomeronasal organ of male Wistar rats to oestrous and dioestrous female Wistar 
      urine led to the appearance of many Fos-ir cells in the rostral region of the 
      periglomerular cell (PGC) layer, but induced few Fos-ir cells in the caudal 
      region. These results suggest that the regionalization of Fos-ir cells after 
      exposure to female urine is remarkable in the PGC layer of the AOB. Sexually 
      experienced male rats have been shown to prefer oestrous to dioestrous female 
      urine, while sexually inexperienced males do not exhibit these preferences. In 
      the present study, we compared the expression of Fos-ir cells in the AOB of 
      sexually experienced and sexually inexperienced male rats following exposure to 
      oestrous and dioestrous urine. In the localized region (lateral and rostral 
      sectors) of the PGC layer, many more Fos-ir cells were expressed in the sexually 
      experienced rats than in the inexperienced rats. These results suggest that 
      sexual experience in males enhances the transmission of reproductively salient 
      information concerning potential oestrous status to a specific PGC region of the 
      AOB.
FAU - Honda, Noriko
AU  - Honda N
AD  - Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 
      060-0812, Japan.
FAU - Sakamoto, Harumi
AU  - Sakamoto H
FAU - Inamura, Kouhei
AU  - Inamura K
FAU - Kashiwayanagi, Makoto
AU  - Kashiwayanagi M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - France
TA  - Eur J Neurosci
JT  - The European journal of neuroscience
JID - 8918110
RN  - 0 (Proto-Oncogene Proteins c-fos)
RN  - 0 (Sex Attractants)
SB  - IM
MH  - Animals
MH  - Female
MH  - Gene Expression/*physiology
MH  - Immunohistochemistry
MH  - Male
MH  - Olfactory Bulb/*metabolism
MH  - Proto-Oncogene Proteins c-fos/*biosynthesis
MH  - Rats
MH  - Rats, Wistar
MH  - Sex Attractants/*metabolism
MH  - Sexual Behavior, Animal/*physiology
MH  - Urine/chemistry
MH  - Vomeronasal Organ
EDAT- 2008/04/17 09:00
MHDA- 2008/07/02 09:00
CRDT- 2008/04/17 09:00
PHST- 2008/04/17 09:00 [pubmed]
PHST- 2008/07/02 09:00 [medline]
PHST- 2008/04/17 09:00 [entrez]
AID - EJN6169 [pii]
AID - 10.1111/j.1460-9568.2008.06169.x [doi]
PST - ppublish
SO  - Eur J Neurosci. 2008 Apr;27(8):1980-8. doi: 10.1111/j.1460-9568.2008.06169.x.