PMID- 18418719 OWN - NLM STAT- MEDLINE DCOM- 20090415 LR - 20211020 IS - 1573-2614 (Electronic) IS - 1387-1307 (Linking) VI - 22 IP - 3 DP - 2008 Jun TI - Non-invasive cardiac output by transthoracic electrical bioimpedence in post-cardiac surgery patients: comparison with thermodilution method. PG - 175-80 LID - 10.1007/s10877-008-9119-y [doi] AB - OBJECTIVE: Thoracic electrical bioimpedance (TEB) cardiac output (CO) is being explored increasingly as a non-invasive alternative to the pulmonary artery catheter (PAC). This study compared TEB-CO measured using a new instrument--NICOMON (Larsen & Toubro Ltd. India) with thermodilution (Td) CO in post-cardiac surgery patients. METHODS: Postoperative cardiac surgical patients requiring a PAC for their management were studied. TEB-CO was measured by passing a 4 mA RMS alternating current across the chest and measuring the analog bioimpedence across the thorax. Kubicek equation was used to estimate TEB-CO. Td-CO was measured using a PAC. Bland-Altman analysis was used to compare paired data. RESULTS: One hundred and ninety-seven pairs of CO measurements were made by the two methods among 35 patients. Mean TEB-CO was 5.15 +/- 1.27 l/min and mean Td-CO was 5.22 +/- 1.28 l/min. Pearson correlation coefficient (r) for these measurements was 0.856 (P < 0.01), with bias -0.0651 l and precision: +/-1.37 l/min. The percentage error of measurement of this precision was 26.44%. Cardiac index also correlated among the two methods (r = 0.789; P = 0.01). CONCLUSIONS: Thoracic electrical bioimpedance cardiac output compares favorably with thermodilution method among post-cardiac surgery patients. Further studies are indi- cated with this instrument to validate its efficacy in various clinical situations and utility in monitoring hemodynamic interventions. FAU - Gujjar, Arunodaya R AU - Gujjar AR AD - Department of Neurology, National Institute of Mental Health & Neurosciences, Hosur Road, Bangalore, 560029, India. grarunoday@yahoo.co.in FAU - Muralidhar, K AU - Muralidhar K FAU - Banakal, Sanjay AU - Banakal S FAU - Gupta, Ratan AU - Gupta R FAU - Sathyaprabha, Talakad N AU - Sathyaprabha TN FAU - Jairaj, P S AU - Jairaj PS LA - eng PT - Comparative Study PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20080417 PL - Netherlands TA - J Clin Monit Comput JT - Journal of clinical monitoring and computing JID - 9806357 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Cardiac Output MH - Cardiography, Impedance/*methods MH - Diagnosis, Computer-Assisted/*methods MH - Female MH - Heart Diseases/*diagnosis/physiopathology/*surgery MH - Humans MH - Male MH - Middle Aged MH - Postoperative Care/methods MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Thermodilution/*methods MH - Young Adult EDAT- 2008/04/18 09:00 MHDA- 2009/04/16 09:00 CRDT- 2008/04/18 09:00 PHST- 2008/02/01 00:00 [received] PHST- 2008/03/26 00:00 [accepted] PHST- 2008/04/18 09:00 [pubmed] PHST- 2009/04/16 09:00 [medline] PHST- 2008/04/18 09:00 [entrez] AID - 10.1007/s10877-008-9119-y [doi] PST - ppublish SO - J Clin Monit Comput. 2008 Jun;22(3):175-80. doi: 10.1007/s10877-008-9119-y. Epub 2008 Apr 17.