PMID- 18420345
OWN - NLM
STAT- MEDLINE
DCOM- 20090615
LR  - 20090623
IS  - 1872-7972 (Electronic)
IS  - 0304-3940 (Linking)
VI  - 437
IP  - 1
DP  - 2008 May 23
TI  - Decreased serum brain-derived neurotrophic factor in trained men.
PG  - 29-32
LID - 10.1016/j.neulet.2008.03.057 [doi]
AB  - The purpose of this study was to clarify the effect of physical activity on the 
      level of serum brain-derived neurotrophic factor (BDNF). The serum BDNF level in 
      trained men who have participated in regular sport activity (n=12) was compared 
      to that in sedentary subjects (n=14). The physical activity levels expressed as 
      total energy expenditure, move-related energy expenditure and walking count in 
      the trained were significantly higher than those in the sedentary. The serum BDNF 
      level in the trained men was found to be lower than that in the sedentary 
      (19.54+/-4.53 ng/ml vs. 23.63+/-2.94 ng/ml, respectively, P<0.01). The serum BDNF 
      level showed a significant negative correlation with daily total energy 
      expenditure (r=-0.507, P<0.05), movement-related energy expenditure (r=-0.503, 
      P<0.05), and walking count (r=-0.480, P<0.05). These results may suggest that 
      vigorous habitual physical activity decrease the serum BDNF level.
FAU - Nofuji, Yu
AU  - Nofuji Y
AD  - Graduate School of Human-Environment Studies, Kyushu University, Kasuga, Fukuoka 
      816-8580, Japan.
FAU - Suwa, Masataka
AU  - Suwa M
FAU - Moriyama, Yoshihiko
AU  - Moriyama Y
FAU - Nakano, Hiroshi
AU  - Nakano H
FAU - Ichimiya, Atsushi
AU  - Ichimiya A
FAU - Nishichi, Reiko
AU  - Nishichi R
FAU - Sasaki, Haruka
AU  - Sasaki H
FAU - Radak, Zsolt
AU  - Radak Z
FAU - Kumagai, Shuzo
AU  - Kumagai S
LA  - eng
PT  - Journal Article
DEP - 20080326
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adult
MH  - Anthropometry
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Energy Metabolism/physiology
MH  - Humans
MH  - Male
MH  - Motor Activity/physiology
MH  - Physical Fitness/*physiology
MH  - Sports
MH  - Walking/physiology
MH  - Young Adult
EDAT- 2008/04/19 09:00
MHDA- 2009/06/16 09:00
CRDT- 2008/04/19 09:00
PHST- 2008/01/30 00:00 [received]
PHST- 2008/03/20 00:00 [revised]
PHST- 2008/03/20 00:00 [accepted]
PHST- 2008/04/19 09:00 [pubmed]
PHST- 2009/06/16 09:00 [medline]
PHST- 2008/04/19 09:00 [entrez]
AID - S0304-3940(08)00384-4 [pii]
AID - 10.1016/j.neulet.2008.03.057 [doi]
PST - ppublish
SO  - Neurosci Lett. 2008 May 23;437(1):29-32. doi: 10.1016/j.neulet.2008.03.057. Epub 
      2008 Mar 26.