PMID- 18424613
OWN - NLM
STAT- MEDLINE
DCOM- 20080805
LR  - 20240316
IS  - 1040-4651 (Print)
IS  - 1532-298X (Electronic)
IS  - 1040-4651 (Linking)
VI  - 20
IP  - 4
DP  - 2008 Apr
TI  - Distinct light-initiated gene expression and cell cycle programs in the shoot 
      apex and cotyledons of Arabidopsis.
PG  - 947-68
LID - 10.1105/tpc.107.057075 [doi]
AB  - In darkness, shoot apex growth is repressed, but it becomes rapidly activated by 
      light. We show that phytochromes and cryptochromes play largely redundant roles 
      in this derepression in Arabidopsis thaliana. We examined the light activation of 
      transcriptional changes in a finely resolved time course, comparing the shoot 
      apex (meristem and leaf primordia) and the cotyledon and found >5700 
      differentially expressed genes. Early events specific to the shoot apices 
      included the repression of genes for Really Interesting New Gene finger proteins 
      and basic domain/leucine zipper and basic helix-loop-helix transcription factors. 
      The downregulation of auxin and ethylene and the upregulation of cytokinin and 
      gibberellin hormonal responses were also characteristic of shoot apices. In the 
      apex, genes involved in ribosome biogenesis and protein translation were rapidly 
      and synchronously induced, simultaneously with cell proliferation genes, 
      preceding visible organ growth. Subsequently, the activation of signaling genes 
      and transcriptional signatures of cell wall expansion, turgor generation, and 
      plastid biogenesis were apparent. Furthermore, light regulates the forms and 
      protein levels of two transcription factors with opposing functions in cell 
      proliferation, E2FB and E2FC, through the Constitutively Photomorphogenic1 
      (COP1), COP9-Signalosome5, and Deetiolated1 light signaling molecules. These data 
      provide the basis for reconstruction of the regulatory networks for 
      light-regulated meristem, leaf, and cotyledon development.
FAU - Lopez-Juez, Enrique
AU  - Lopez-Juez E
AD  - School of Biological Sciences, Royal Holloway, University of London, Egham, 
      Surrey TW20 0EX, United Kingdom. e.lopez@rhul.ac.uk
FAU - Dillon, Edyta
AU  - Dillon E
FAU - Magyar, Zoltan
AU  - Magyar Z
FAU - Khan, Safina
AU  - Khan S
FAU - Hazeldine, Saul
AU  - Hazeldine S
FAU - de Jager, Sarah M
AU  - de Jager SM
FAU - Murray, James A H
AU  - Murray JA
FAU - Beemster, Gerrit T S
AU  - Beemster GT
FAU - Bogre, Laszlo
AU  - Bogre L
FAU - Shanahan, Hugh
AU  - Shanahan H
LA  - eng
GR  - BB/D017599/1/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - BBS/B/13314/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080418
PL  - England
TA  - Plant Cell
JT  - The Plant cell
JID - 9208688
RN  - 0 (Photosynthetic Reaction Center Complex Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Arabidopsis/cytology/genetics/*radiation effects
MH  - Cell Cycle/*radiation effects
MH  - Cotyledon/*cytology
MH  - Gene Expression/*radiation effects
MH  - Genes, Plant
MH  - *Light
MH  - Multigene Family
MH  - Photosynthetic Reaction Center Complex Proteins/physiology
MH  - Plant Shoots/*cytology
MH  - Polymerase Chain Reaction
MH  - Transcription, Genetic/radiation effects
PMC - PMC2390750
EDAT- 2008/04/22 09:00
MHDA- 2008/08/06 09:00
PMCR- 2009/04/01
CRDT- 2008/04/22 09:00
PHST- 2008/04/22 09:00 [pubmed]
PHST- 2008/08/06 09:00 [medline]
PHST- 2008/04/22 09:00 [entrez]
PHST- 2009/04/01 00:00 [pmc-release]
AID - tpc.107.057075 [pii]
AID - 057075 [pii]
AID - 10.1105/tpc.107.057075 [doi]
PST - ppublish
SO  - Plant Cell. 2008 Apr;20(4):947-68. doi: 10.1105/tpc.107.057075. Epub 2008 Apr 18.