PMID- 18430137
OWN - NLM
STAT- MEDLINE
DCOM- 20080715
LR  - 20080514
IS  - 1365-2958 (Electronic)
IS  - 0950-382X (Linking)
VI  - 68
IP  - 5
DP  - 2008 Jun
TI  - Mini-III, a fourth class of RNase III catalyses maturation of the Bacillus 
      subtilis 23S ribosomal RNA.
PG  - 1073-6
LID - 10.1111/j.1365-2958.2008.06203.x [doi]
AB  - Ribonuclease III (RNase III) type of enzymes are double-stranded RNA 
      (dsRNA)-specific endoribonucleases that have important roles in RNA maturation 
      and mRNA decay. They are involved in processing precursors of ribosomal RNA 
      (rRNA) in bacteria as well as precursors of short interfering RNAs (siRNAs) and 
      microRNAs (miRNAs) in eukaryotes. RNase III proteins have been grouped in three 
      major classes according to their domain organization. In this issue of Molecular 
      Microbiology, Redko et al. identified a novel class of bacterial RNase III, named 
      Mini-III, consisting only of the RNase III catalytic domain and functioning in 
      the maturation of the 23S rRNA in Bacillus subtilis. Its absence from 
      proteobacteria reveals that this step is mechanistically different from the 
      corresponding step in Escherichia coli. The fact that Mini-III orthologues are 
      present in unicellular photosynthetic eukaryotes and in plants opens new 
      opportunities for functional studies of this type of RNases.
FAU - Olmedo, Gabriela
AU  - Olmedo G
AD  - Departamento de Ingenieria Genetica de Plantas, Cinvestav, Campus Guanajuato, Km 
      9.6 Libramiento Norte, 36821, Irapuato, Guanajuato, Mexico. 
      golmedo@ira.cinvestav.mx
FAU - Guzman, Plinio
AU  - Guzman P
LA  - eng
PT  - Journal Article
DEP - 20080421
PL  - England
TA  - Mol Microbiol
JT  - Molecular microbiology
JID - 8712028
RN  - 0 (RNA, Bacterial)
RN  - 0 (RNA, Ribosomal, 23S)
RN  - EC 2.7.7.- (Nucleotidyltransferases)
RN  - EC 2.7.7.- (mRNA maturase)
RN  - EC 3.1.- (Endoribonucleases)
RN  - EC 3.1.26.3 (Ribonuclease III)
SB  - IM
MH  - Bacillus subtilis/*enzymology/genetics
MH  - Endoribonucleases/metabolism
MH  - Nucleotidyltransferases/metabolism
MH  - RNA, Bacterial/chemistry/*metabolism
MH  - RNA, Ribosomal, 23S/chemistry/*metabolism
MH  - Ribonuclease III/chemistry/*metabolism
EDAT- 2008/04/24 09:00
MHDA- 2008/07/17 09:00
CRDT- 2008/04/24 09:00
PHST- 2008/04/24 09:00 [pubmed]
PHST- 2008/07/17 09:00 [medline]
PHST- 2008/04/24 09:00 [entrez]
AID - MMI6203 [pii]
AID - 10.1111/j.1365-2958.2008.06203.x [doi]
PST - ppublish
SO  - Mol Microbiol. 2008 Jun;68(5):1073-6. doi: 10.1111/j.1365-2958.2008.06203.x. Epub 
      2008 Apr 21.