PMID- 18434223
OWN - NLM
STAT- MEDLINE
DCOM- 20080915
LR  - 20080616
IS  - 1096-7206 (Electronic)
IS  - 1096-7192 (Linking)
VI  - 94
IP  - 3
DP  - 2008 Jul
TI  - Inherited endocrinopathies: an update.
PG  - 271-82
LID - 10.1016/j.ymgme.2008.03.006 [doi]
AB  - Inherited endocrinopathies, including multiple endocrine neoplasia type 1 
      (MEN-1), multiple endocrine neoplasia type 2 syndromes (MEN-2A, MEN-2B, familial 
      medullary thyroid carcinoma), and inherited syndromes with pheochromocytoma (von 
      Hippel-Lindau disease, neurofibromatosis type 1, others), comprise a 
      heterogeneous group of cancer susceptibility syndromes that affect one or more 
      components of the endocrine system. During the past several years, novel findings 
      regarding genotype-phenotype correlation have highlighted the importance of 
      establishing a genetic diagnosis in the treatment of these diseases. Here, we 
      present a case-based review of recent advances in the genetics, diagnosis and 
      management of inherited endocrinopathies.
FAU - Lewis, Catherine E
AU  - Lewis CE
AD  - Department of General Surgery, David Geffen School of Medicine, University of 
      California, 10833 Le Conte Avenue, Los Angeles, CA 90095-6904, USA.
FAU - Yeh, Michael W
AU  - Yeh MW
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20080422
PL  - United States
TA  - Mol Genet Metab
JT  - Molecular genetics and metabolism
JID - 9805456
SB  - IM
MH  - Carcinoma, Medullary/diagnosis/epidemiology
MH  - Comorbidity
MH  - Endocrine System Diseases/*diagnosis/*genetics/*therapy
MH  - Genetic Diseases, Inborn/diagnosis/therapy
MH  - Humans
MH  - Models, Biological
MH  - Multiple Endocrine Neoplasia Type 1/diagnosis/epidemiology/genetics
MH  - Multiple Endocrine Neoplasia Type 2a/diagnosis/epidemiology/genetics
MH  - Paraganglioma/diagnosis/epidemiology/etiology
MH  - Pheochromocytoma/diagnosis/epidemiology/etiology
MH  - Thyroid Neoplasms/diagnosis/epidemiology
RF  - 83
EDAT- 2008/04/25 09:00
MHDA- 2008/09/16 09:00
CRDT- 2008/04/25 09:00
PHST- 2007/12/20 00:00 [received]
PHST- 2008/03/10 00:00 [revised]
PHST- 2008/03/10 00:00 [accepted]
PHST- 2008/04/25 09:00 [pubmed]
PHST- 2008/09/16 09:00 [medline]
PHST- 2008/04/25 09:00 [entrez]
AID - S1096-7192(08)00075-9 [pii]
AID - 10.1016/j.ymgme.2008.03.006 [doi]
PST - ppublish
SO  - Mol Genet Metab. 2008 Jul;94(3):271-82. doi: 10.1016/j.ymgme.2008.03.006. Epub 
      2008 Apr 22.