PMID- 18438438
OWN - NLM
STAT- MEDLINE
DCOM- 20080709
LR  - 20220409
IS  - 0831-2796 (Print)
IS  - 0831-2796 (Linking)
VI  - 51
IP  - 5
DP  - 2008 May
TI  - Microsatellite accumulation on the Y chromosome in Silene latifolia.
PG  - 350-6
LID - 10.1139/G08-024 [doi]
AB  - The dioecious plant Silene latifolia possesses evolutionarily young sex 
      chromosomes, and so serves as a model system to study the early stages of sex 
      chromosome evolution. Sex chromosomes often differ distinctly from autosomes in 
      both their structure and their patterns of evolution. The S. latifolia Y 
      chromosome is particularly unique owing to its large size, which contrasts with 
      the size of smaller, degenerate mammalian Y chromosomes. It is thought that the 
      suppression of recombination on the S. latifolia Y chromosome could have resulted 
      in the accumulation of repetitive sequences that account for its large size. Here 
      we used fluorescence in situ hybridization (FISH) to study the chromosomal 
      distribution of various microsatellites in S. latifolia including all possible 
      mono-, di-, and tri-nucleotides. Our results demonstrate that a majority of 
      microsatellites are accumulated on the q arm of the Y chromosome, which stopped 
      recombining relatively recently and has had less time to accumulate repetitive 
      DNA sequences compared with the p arm. Based on these results we can speculate 
      that microsatellites have accumulated in regions that predate the genome 
      expansion, supporting the view that the accumulation of repetitive DNA sequences 
      occurred prior to, not because of, the degeneration of genes.
FAU - Kubat, Zdenek
AU  - Kubat Z
AD  - Laboratory of Plant Developmental Genetics, Institute of Biophysics, Academy of 
      Sciences of the Czech Republic, Brno, Czech Republic.
FAU - Hobza, Roman
AU  - Hobza R
FAU - Vyskot, Boris
AU  - Vyskot B
FAU - Kejnovsky, Eduard
AU  - Kejnovsky E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Canada
TA  - Genome
JT  - Genome
JID - 8704544
SB  - IM
MH  - *Chromosomes, Plant
MH  - In Situ Hybridization, Fluorescence
MH  - Metaphase
MH  - Microsatellite Repeats/*genetics
MH  - Silene/*genetics
EDAT- 2008/04/29 09:00
MHDA- 2008/07/10 09:00
CRDT- 2008/04/29 09:00
PHST- 2008/04/29 09:00 [pubmed]
PHST- 2008/07/10 09:00 [medline]
PHST- 2008/04/29 09:00 [entrez]
AID - g08-024 [pii]
AID - 10.1139/G08-024 [doi]
PST - ppublish
SO  - Genome. 2008 May;51(5):350-6. doi: 10.1139/G08-024.