PMID- 18441471 OWN - NLM STAT- MEDLINE DCOM- 20080911 LR - 20190819 IS - 1346-9843 (Print) IS - 1346-9843 (Linking) VI - 72 IP - 5 DP - 2008 May TI - Infliximab treatment for refractory Kawasaki disease with coronary artery aneurysm. PG - 850-2 AB - Tumor necrosis factor-alpha (TNF-alpha) is considered to be 1 of the factors that induce vasculitis, including coronary artery aneurysm (CA), in Kawasaki disease (KD), because the blood concentration of TNF-alpha is higher in patients with CA compared with those without. Therefore, an anti-TNF-alphaagent (infliximab) was administered to a 1-month-old girl with refractory KD complicated by CA and subsequently, the CA improved and KD was controlled without complications 20 months after the onset. FAU - Oishi, Taku AU - Oishi T AD - Department of Pediatrics, Kochi National Hospital, Kochi, Japan. FAU - Fujieda, Mikiya AU - Fujieda M FAU - Shiraishi, Taisuke AU - Shiraishi T FAU - Ono, Miki AU - Ono M FAU - Inoue, Kazuo AU - Inoue K FAU - Takahashi, Akiyoshi AU - Takahashi A FAU - Ogura, Hideo AU - Ogura H FAU - Wakiguchi, Hiroshi AU - Wakiguchi H LA - eng PT - Case Reports PT - Journal Article PL - Japan TA - Circ J JT - Circulation journal : official journal of the Japanese Circulation Society JID - 101137683 RN - 0 (Anti-Inflammatory Agents) RN - 0 (Antibodies, Monoclonal) RN - B72HH48FLU (Infliximab) SB - IM EIN - Circ J. 2008 Jul;72(7):1212 MH - Anti-Inflammatory Agents/*administration & dosage MH - Antibodies, Monoclonal/*administration & dosage MH - Coronary Aneurysm/complications/diagnostic imaging/*drug therapy MH - Drug Resistance MH - Echocardiography MH - Female MH - Humans MH - Infant, Newborn MH - Infliximab MH - Mucocutaneous Lymph Node Syndrome/complications/diagnostic imaging/*drug therapy EDAT- 2008/04/29 09:00 MHDA- 2008/09/13 09:00 CRDT- 2008/04/29 09:00 PHST- 2008/04/29 09:00 [pubmed] PHST- 2008/09/13 09:00 [medline] PHST- 2008/04/29 09:00 [entrez] AID - JST.JSTAGE/circj/72.850 [pii] AID - 10.1253/circj.72.850 [doi] PST - ppublish SO - Circ J. 2008 May;72(5):850-2. doi: 10.1253/circj.72.850.