PMID- 18441768 OWN - NLM STAT- MEDLINE DCOM- 20080703 LR - 20181201 IS - 0011-4162 (Print) IS - 0011-4162 (Linking) VI - 81 IP - 2 DP - 2008 Feb TI - Terbinafine-induced subacute cutaneous lupus erythematosus. PG - 156-7 AB - Terbinafine is a synthetic oral allylamine that is used for systemic treatment of microscopy- or culture-proven dermatophyte infections of skin and nails. It is normally well-tolerated and side effects include transient gastrointestinal symptoms and skin reactions that can occur in up to 2.3% of treated patients. Subacute cutaneous lupus erythematosus (SCLE) is a skin reaction that has been reported secondary to use of a variety of drugs. The number of reports of SCLE with terbinafine is limited. We demonstrate 2 patients in one dermatology clinic who presented with a predisposing autoimmune diathesis within 3 months of each other. FAU - Hivnor, Chad M AU - Hivnor CM AD - Wilford Hall Medical Center, Lackland Air Force Base, Lackland AFB, TX 78236-9908, USA. chivnor@pol.net FAU - Hudkins, Matthew L AU - Hudkins ML FAU - Bonner, Bert AU - Bonner B LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Cutis JT - Cutis JID - 0006440 RN - 0 (Antifungal Agents) RN - 0 (Naphthalenes) RN - G7RIW8S0XP (Terbinafine) SB - IM MH - Administration, Oral MH - Aged MH - Antifungal Agents/administration & dosage/*adverse effects MH - Dermatomycoses/drug therapy MH - Female MH - Granuloma/drug therapy MH - Humans MH - Lupus Erythematosus, Cutaneous/*chemically induced MH - Middle Aged MH - Naphthalenes/administration & dosage/*adverse effects MH - Skin Diseases/drug therapy MH - Terbinafine EDAT- 2008/04/30 09:00 MHDA- 2008/07/04 09:00 CRDT- 2008/04/30 09:00 PHST- 2008/04/30 09:00 [pubmed] PHST- 2008/07/04 09:00 [medline] PHST- 2008/04/30 09:00 [entrez] PST - ppublish SO - Cutis. 2008 Feb;81(2):156-7.