PMID- 18442726
OWN - NLM
STAT- MEDLINE
DCOM- 20080626
LR  - 20171116
IS  - 1557-3117 (Electronic)
IS  - 1053-2498 (Linking)
VI  - 27
IP  - 5
DP  - 2008 May
TI  - Successful bridge to transplant in a highly sensitized patient with a complicated 
      pump pocket infection.
PG  - 568-71
LID - 10.1016/j.healun.2008.02.006 [doi]
AB  - A 32-year-old man with doxorubicin-induced cardiomyopathy presented in 
      cardiogenic shock. He underwent placement of a Novacor (WorldHeart, Inc., 
      Oakland, CA) left ventricular assist device as a bridge to transplant. 
      Post-operatively he developed a pump pocket infection and dehiscence of his 
      abdominal wound with exposure of the pump. This was treated with irrigation and 
      drainage, antibiotic bead placement and flap closure. Both pre- and 
      post-operative panel-reactive antibodies (PRA) were elevated. He underwent 
      desensitization with intravenous immune globulin (IVIg), rituximab, mycophenolate 
      mofetil and pre-operative plasmapheresis. A donor heart was identified and found 
      to be acceptable by virtual crossmatch. He was transplanted and is doing well 
      with normal graft function at >1 year post-operatively.
FAU - McGee, Edwin C Jr
AU  - McGee EC Jr
AD  - Division of Cardiothoracic Surgery, Bluhm Cardiovascular Institute, Northwestern 
      Memorial Hospital, 201 East Huron Street, Galter 11-140, Chicago, IL 60611, USA. 
      emcgee@nmh.org
FAU - Cotts, William
AU  - Cotts W
FAU - Tambur, Anat R
AU  - Tambur AR
FAU - Friedewald, John
AU  - Friedewald J
FAU - Kim, John
AU  - Kim J
FAU - O'Connell, John
AU  - O'Connell J
FAU - Wallace, Suzanne
AU  - Wallace S
FAU - McCarthy, Patrick M
AU  - McCarthy PM
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Heart Lung Transplant
JT  - The Journal of heart and lung transplantation : the official publication of the 
      International Society for Heart Transplantation
JID - 9102703
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antibiotics, Antineoplastic)
RN  - 80168379AG (Doxorubicin)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/administration & dosage
MH  - Antibiotics, Antineoplastic/adverse effects
MH  - Bone Neoplasms/drug therapy
MH  - Cardiomyopathies/chemically induced/*surgery
MH  - Doxorubicin/adverse effects
MH  - Drainage
MH  - Heart Transplantation/*immunology
MH  - Heart-Assist Devices/*adverse effects
MH  - Histocompatibility/immunology
MH  - Humans
MH  - Male
MH  - Osteosarcoma/drug therapy
MH  - Prosthesis-Related Infections/etiology/*therapy
MH  - Shock, Cardiogenic/surgery
MH  - Surgical Wound Dehiscence/etiology/therapy
MH  - Surgical Wound Infection/etiology/therapy
MH  - Therapeutic Irrigation
MH  - Transfusion Reaction
MH  - Treatment Outcome
EDAT- 2008/04/30 09:00
MHDA- 2008/06/27 09:00
CRDT- 2008/04/30 09:00
PHST- 2007/11/01 00:00 [received]
PHST- 2008/01/22 00:00 [revised]
PHST- 2008/02/06 00:00 [accepted]
PHST- 2008/04/30 09:00 [pubmed]
PHST- 2008/06/27 09:00 [medline]
PHST- 2008/04/30 09:00 [entrez]
AID - S1053-2498(08)00139-3 [pii]
AID - 10.1016/j.healun.2008.02.006 [doi]
PST - ppublish
SO  - J Heart Lung Transplant. 2008 May;27(5):568-71. doi: 
      10.1016/j.healun.2008.02.006.