PMID- 18444533 OWN - NLM STAT- MEDLINE DCOM- 20080603 LR - 20080430 IS - 0041-4131 (Print) IS - 0041-4131 (Linking) VI - 86 IP - 2 DP - 2008 Feb TI - Clinicopathological characteristics of synchronous bilateral breast carcinomas. Report of 30 patients. PG - 155-9 AB - AIM: The objective of this study is to determine the clinicopathologic characteristics; incidence and prognosis value of synchronous bilateral breast carcinoma (SBBC). METHODS: This is a retrospective study done in Salah Azaiz Institute of Tunis about 30 patients with synchronous bilateral breast carcinomas diagnosed and treated over a 21-years period going from 1977 to 1997. The definition of synchronous breast lesions is the developpement of the contralateral breast cancer within 6 months. RESULTS: Median age was 49 years. The incidence of SBBC was 0.52%. History family was noted in 3% of our population. Mean tumor size was 40 mm (15-145). Breast conserving therapy was done in 16% of cases (9 patients). Five-year overall survival was 40%. Five year survival rates were 72 and 17% for stage II and III, respectively. Main prognostic factors for survival were lymph node involvement (P=0.004) and disease stage (P=0.02). CONCLUSION: Synchronous bilateral breast carcinoma is a rare entity, with a problem of definition concerning the delay of bilaterlisation. Their prognosis is similar to that of unilateral breast carcinoma patients of equal stage. Hence, breast conserving therapy can be used s fely if indicated. FAU - Ben Hassouna, Jamel AU - Ben Hassouna J AD - Department of surgical oncology, Salah Azaiz Institute, Tunis, Tunisie. FAU - Damak, Tarak AU - Damak T FAU - Chargui, Riadh AU - Chargui R FAU - Slimene, Maher AU - Slimene M FAU - Chkir, Amine AU - Chkir A FAU - Ayadi, Mohamed Ali AU - Ayadi MA FAU - Mtallah, Mohamed AU - Mtallah M FAU - Hechiche, Monia AU - Hechiche M FAU - Gamoudi, Amor AU - Gamoudi A FAU - Khomsi, Fethi AU - Khomsi F FAU - Ben Dhiab, Tarak AU - Ben Dhiab T FAU - Rahal, Khaled AU - Rahal K LA - eng PT - Journal Article PL - Tunisia TA - Tunis Med JT - La Tunisie medicale JID - 0413766 SB - IM MH - Adult MH - Aged MH - Breast Neoplasms/mortality/*pathology/surgery MH - Carcinoma/mortality/*pathology/surgery MH - Female MH - Humans MH - Mastectomy, Segmental MH - Middle Aged MH - Prognosis MH - Retrospective Studies EDAT- 2008/05/01 09:00 MHDA- 2008/06/05 09:00 CRDT- 2008/05/01 09:00 PHST- 2008/05/01 09:00 [pubmed] PHST- 2008/06/05 09:00 [medline] PHST- 2008/05/01 09:00 [entrez] PST - ppublish SO - Tunis Med. 2008 Feb;86(2):155-9.