PMID- 18444582
OWN - NLM
STAT- MEDLINE
DCOM- 20080612
LR  - 20220331
IS  - 1025-9589 (Print)
IS  - 1025-9589 (Linking)
VI  - 19
IP  - 3
DP  - 2007 Jul-Sep
TI  - Early left ventricular remodeling after aortic valve replacement.
PG  - 10-4
AB  - BACKGROUND: Aortic valve disease is associated with eccentric or concentric left 
      ventricular (LV) hypertrophy and changes in the LV mass. The relationship between 
      LV mass and function and the effect of LV remodeling after aortic valve 
      replacement (AVR), in patients with aortic valve disease needs evaluation, that 
      is largely unknown in our population. The aim of this study was to evaluate the 
      effect of AVR on LV remodeling, in patients with aortic valve disease. METHODS: 
      Fifty patients with aortic valve disease were studied using transthoracic 
      echocardiography to assess LV mass before AVR and compared with early 
      postoperative changes in the LV dimensions and function. LV mass was studied 
      preoperatively and before discharge in 50 consecutive patients undergoing 
      isolated aortic valve replacement. RESULTS: Out of fifty patients, 47 (94%) were 
      male and 03 (6%) were female. Mean age of the patients was 40.42 years. 22 (44%) 
      had isolated aortic stenosis (AS), 16 (32%) patients had isolated aortic 
      regurgitation (AR) and 12 (24%) patients had mixed aortic valve disease (MAVD). 
      02 (4%) patients died. LV mass regression was studied in all the patients. In 
      group A, with aortic stenosis, LV regressed to 69.88 gm (mean) with maximum of 
      156.88 gms and minimum of 0.00 gms (SD 43.67 gms, p value = 0.001). In group B, 
      with aortic regurgitation, LV mass regressed to 203.96 gms (mean) with maximum 
      453.79 gms and minimum of 45.65 gms (SD 95.33, p value = < 0.001). In group C, 
      with mixed aortic valve disease, postoperatively LV mass regressed to 122.94 gms 
      (mean) with minimum 9.57 and maximum of 224.75 gms (SD 69.53, p value = 0.524). 
      CONCLUSION: There was significant early LV mass regression after aortic valve 
      replacement in patients with pre existing aortic valve disease. However, it was 
      noticed that LV mass regressed in all patients except no significant changes in 
      LV wall thickness (hypertrophy).
FAU - Ahmad, Naseem
AU  - Ahmad N
AD  - Department of Cardiac Surgery, Punjab Institute of Cardiology, Lahore, Pakistan.
FAU - Shahbaz, Ahmad
AU  - Shahbaz A
FAU - Ghaffar, Abdul
AU  - Ghaffar A
FAU - Tufail, Zafar
AU  - Tufail Z
FAU - Waheed, Abdul
AU  - Waheed A
FAU - Khan, Jawad Sajid
AU  - Khan JS
LA  - eng
PT  - Journal Article
PL  - Pakistan
TA  - J Ayub Med Coll Abbottabad
JT  - Journal of Ayub Medical College, Abbottabad : JAMC
JID - 8910750
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve Insufficiency/surgery
MH  - Aortic Valve Stenosis/surgery
MH  - Female
MH  - *Heart Valve Prosthesis Implantation
MH  - Heart Ventricles/diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Period
MH  - Time Factors
MH  - Ultrasonography
MH  - Ventricular Remodeling
EDAT- 2008/05/01 09:00
MHDA- 2008/06/13 09:00
CRDT- 2008/05/01 09:00
PHST- 2008/05/01 09:00 [pubmed]
PHST- 2008/06/13 09:00 [medline]
PHST- 2008/05/01 09:00 [entrez]
PST - ppublish
SO  - J Ayub Med Coll Abbottabad. 2007 Jul-Sep;19(3):10-4.