PMID- 18448445
OWN - NLM
STAT- MEDLINE
DCOM- 20080821
LR  - 20080709
IS  - 1475-3162 (Electronic)
IS  - 0003-4878 (Linking)
VI  - 52
IP  - 5
DP  - 2008 Jul
TI  - Size-separated sampling and analysis of isocyanates in workplace aerosols--Part 
      II: aging of aerosols from thermal degradation of polyurethane.
PG  - 375-83
LID - 10.1093/annhyg/men018 [doi]
AB  - A new type of isocyanate sampler has been used to investigate aging aerosols 
      generated during thermal degradation of polyurethane (PUR). The sampler consists 
      of a denuder connected in series with a three-stage cascade impactor and a 
      filter. The denuder collects gas-phase isocyanates. The three impactor stages had 
      cut-off diameters (d(50)) of 2.5, 1.0 and 0.5 mum, respectively. The end filter 
      collects particles <0.5 mum. For derivatization of isocyanates in the sampler, 
      di-n-butylamine mixed with an equimolar amount of acetic acid was used for 
      impregnation of the sampler stages. Consecutive sampling using three 
      denuder-impactor samplers was performed in a test chamber, with a total sampling 
      time of 9 min. Analysis of air samples was performed using liquid 
      chromatography-mass spectrometry (LC-MS)/MS. Particle size measurements were 
      performed using a scanning mobility particle sizer (SMPS). A time-dependent 
      behavior was observed for aromatic diisocyanates during aging of the aerosol. 
      Thermal degradation of different PUR materials showed different distribution of 
      isocyanates between gas and particles. Aromatic diisocyanates (toluene 
      diisocyanate (TDI) and methylene diphenyl diisocyanate) were initially in gas 
      phase and associated to very small particles. After a few minutes most of these 
      isocyanates were associated with particles <1 mum. Monoisocyanates and 
      hexamethylene diisocyanate (HDI) were not found to be associated with particles.
FAU - Dahlin, Jakob
AU  - Dahlin J
AD  - Work Environment Chemistry, Stockholm University, PO Box 460, S-281 24 
      Hassleholm, Sweden.
FAU - Spanne, Marten
AU  - Spanne M
FAU - Dalene, Marianne
AU  - Dalene M
FAU - Karlsson, Daniel
AU  - Karlsson D
FAU - Skarping, Gunnar
AU  - Skarping G
LA  - eng
PT  - Journal Article
DEP - 20080430
PL  - England
TA  - Ann Occup Hyg
JT  - The Annals of occupational hygiene
JID - 0203526
RN  - 0 (Aerosols)
RN  - 0 (Air Pollutants, Occupational)
RN  - 0 (Isocyanates)
RN  - 0 (Polyurethanes)
SB  - IM
MH  - Aerosols/analysis
MH  - Air Pollutants, Occupational/*analysis
MH  - Chemical Industry
MH  - Environmental Monitoring/*methods
MH  - Humans
MH  - Inhalation Exposure/analysis
MH  - Isocyanates/*analysis
MH  - Occupational Exposure/*analysis
MH  - Particle Size
MH  - Polyurethanes/chemistry
EDAT- 2008/05/02 09:00
MHDA- 2008/08/22 09:00
CRDT- 2008/05/02 09:00
PHST- 2008/05/02 09:00 [pubmed]
PHST- 2008/08/22 09:00 [medline]
PHST- 2008/05/02 09:00 [entrez]
AID - men018 [pii]
AID - 10.1093/annhyg/men018 [doi]
PST - ppublish
SO  - Ann Occup Hyg. 2008 Jul;52(5):375-83. doi: 10.1093/annhyg/men018. Epub 2008 Apr 
      30.